iCELLis® Bioreactor product photo Primary L

iCELLis® Bioreactor

The iCELLis bioreactor system is an automated, single-use, fixed-bed bioreactor that provides excellent cell growth conditions for adherent cells.

  • Cell culture process simplification, from vial to product
  • Fully-integrated, single-use bioreactor with disposable, pre-installed calibrated probes
  • Unique waterfall system for optimal oxygenation and CO2 stripping
  • Straightforward implementation for faster process development
  • Predictable scalability from R&D to manufacturing
  • Compact high-cell-density, fixed-bed bioreactor providing a significant increase in volumetric
  • productivity vs. traditional stirred tanks
  • Significant decrease in operational costs and capital investments vs. classical 2D flatware
Full information about this product is available from the product datasheet.


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Description

The iCELLis bioreactor system is an automated, single-use, fixed-bed bioreactor that provides excellent cell growth conditions for adherent cells.

  • Cell culture process simplification, from vial to product
  • Fully-integrated, single-use bioreactor with disposable, pre-installed calibrated probes
  • Unique waterfall system for optimal oxygenation and CO2 stripping
  • Straightforward implementation for faster process development
  • Predictable scalability from R&D to manufacturing
  • Compact high-cell-density, fixed-bed bioreactor providing a significant increase in volumetric
  • productivity vs. traditional stirred tanks
  • Significant decrease in operational costs and capital investments vs. classical 2D flatware
Full information about this product is available from the product datasheet.
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Applications

The iCELLis bioreactor systems are available in two formats:

  • The iCELLis Nano system for feasibility studies and small-scale production (up to 4 m2)
  • The iCELLis 500 system for industrial scale manufacturing (up to 500 m2)
 

iCELLis Nano system

iCELLis 500 system

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Performance

The fixed-bed design of the iCELLis system makes it the perfect solution for industrialization of adherent cell processes and virus production for both gene therapy and vaccines, providing a large cell growth surface area while keeping the footprint very small. In only 25 L of fixed-bed volume, the iCELLis system accommodates up to 500 m2 of growth area, which, when compared with available surfaces of multitray systems and roller bottles, corresponds to a huge reduction in volumes. The iCELLis 500/500 m2 system is equivalent to 794 cell stacks with 10 trays and 5,882 roller bottles at 850 cm2 each. In addition to volume reduction, the use of a filled, fixed-bed in the iCELLis system enables higher specific productivity than in other culture systems.

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Additional Information

Video

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Application
CELL CULTURE - BIOREACTORS
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Segment
Cell Culture