Supor® EAV Membrane Filter Cartridges product photo Primary L

Supor® EAV Membrane Filter Cartridges

Pall Supor® EAV filters are designed for effective bioburden and particle control.  The Pall-patented Supor machV membrane incorporated in these filters ensures high throughputs and flow rates when utilized for the protection of buffers and biological process fluids. 

Supor EAV filters allow for reduced sizing of filter systems with improved process efficiencies when use of validated sterilizing grade filters is not essential, but reliable bioburden control is.  Supor EAV filters are also effective prefilters for protection and extended life of 0.2 µm sterilizing grade and finer membrane filters where required.

Pall’s AB style filters are disposable 254mm (10 inch) modular element cartridges assembled in 254, 508, 762 and 1016 mm lengths to be used with stainless steel housing assemblies, most suitable for medium to large scale manufacturing operations (100 L to >1000 L). With Code 7 fittings as standard, these are the most versatile filtration units in Pall’s range, and incorporate a broader range of filtration media than any other filter type. These filters, when encapsulated, become the Kleenpak™ Nova capsule format.

Features and Benefits of Supor EAV Filters

  • Hydrophilic, controlled asymmetric polyethersulfone (PES) membrane ensures high microbial and particulate reduction with outstanding service life
  • Bacterial titer reduction in excess of 6 log for Brevundimonas diminuta ensures low bioburden levels in filtrate regardless of bacterial loading
  • Broad pH compatibility for processing a wide range of buffers and other fluids
  • High membrane area featuring Pall-patented Ultipleat® construction combined with a narrow diameter core guarantees high flow rates, increased robustness and smaller multicartridge assemblies.
  • Available in Kleenpak™ capsule formats to eliminate housing cleaning and associated validation, for ease of use and integration into single use disposable systems
  • Low binding polyethersulfone membrane for maximum transmission of proteins

Quality Standards

  • 100% integrity tested
  • Manufactured for use in conformance with cGMP
  • Each filter is fully traceable by individual marked lot and serial number
  • ISO 9001 Certified Quality System
  • Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics
  • Certificate of Test provided includes:
    • Fabrication Integrity 
    • Bacterial Retention 
    • Materials of constructions
    • Effluent quality for cleanliness, TOC and water conductivity, pH and pyrogens


 View additional Sterile Filtration and Bioburden Control products and technologies.

Products in this datasheet may be covered by one or more patents including :
EP 0 667 800
EP 0 982 061
EP 1 380 331
US 5,543,047
US 5,690,765
US 5,725,784
US 6,113,784
US 7,083,564
US 7,318,800



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Description
Pall Supor® EAV filters are designed for effective bioburden and particle control.  The Pall-patented Supor machV membrane incorporated in these filters ensures high throughputs and flow rates when utilized for the protection of buffers and biological process fluids. 

Supor EAV filters allow for reduced sizing of filter systems with improved process efficiencies when use of validated sterilizing grade filters is not essential, but reliable bioburden control is.  Supor EAV filters are also effective prefilters for protection and extended life of 0.2 µm sterilizing grade and finer membrane filters where required.

Pall’s AB style filters are disposable 254mm (10 inch) modular element cartridges assembled in 254, 508, 762 and 1016 mm lengths to be used with stainless steel housing assemblies, most suitable for medium to large scale manufacturing operations (100 L to >1000 L). With Code 7 fittings as standard, these are the most versatile filtration units in Pall’s range, and incorporate a broader range of filtration media than any other filter type. These filters, when encapsulated, become the Kleenpak™ Nova capsule format.

Features and Benefits of Supor EAV Filters

  • Hydrophilic, controlled asymmetric polyethersulfone (PES) membrane ensures high microbial and particulate reduction with outstanding service life
  • Bacterial titer reduction in excess of 6 log for Brevundimonas diminuta ensures low bioburden levels in filtrate regardless of bacterial loading
  • Broad pH compatibility for processing a wide range of buffers and other fluids
  • High membrane area featuring Pall-patented Ultipleat® construction combined with a narrow diameter core guarantees high flow rates, increased robustness and smaller multicartridge assemblies.
  • Available in Kleenpak™ capsule formats to eliminate housing cleaning and associated validation, for ease of use and integration into single use disposable systems
  • Low binding polyethersulfone membrane for maximum transmission of proteins

Quality Standards

  • 100% integrity tested
  • Manufactured for use in conformance with cGMP
  • Each filter is fully traceable by individual marked lot and serial number
  • ISO 9001 Certified Quality System
  • Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics
  • Certificate of Test provided includes:
    • Fabrication Integrity 
    • Bacterial Retention 
    • Materials of constructions
    • Effluent quality for cleanliness, TOC and water conductivity, pH and pyrogens


 View additional Sterile Filtration and Bioburden Control products and technologies.

Products in this datasheet may be covered by one or more patents including :
EP 0 667 800
EP 0 982 061
EP 1 380 331
US 5,543,047
US 5,690,765
US 5,725,784
US 6,113,784
US 7,083,564
US 7,318,800

Specifications

Materials of Construction

 

 
 Membrane   Hydrophilic, asymmetric polyethersulfone (0.2 µm particulate rating)
 Drainage Layers  Polypropylene
 End Cap and Cage  Polypropylene
 Core  Polypropylene 
 Adapter  Polypropylene with internal stainless steel reinforcing ring
 
 

Effective Surface Area

 

 
AB05UEAV* Typically 0.51 m (5.5 ft)
AB1UEAV* Typically 1.06 m (11.4 ft)
AB2UEAV* Typically 2.12 m (22.8 ft)
AB3UEAV*   Typically 3.18 m (34.2 ft)
AB4UEAV* Typically 4.24 m (45.6 ft)
 

 

Extractables

 
 Typical Extractables per 254mm (10 inch) Module  < 50 mg in water at 20oC after a 1 hour autoclave cycle and 4 hours extraction time
 

Steam Life1

 
 Typical Cumulative Steam Life  10 hours (1 hour cycles) at 125oC
 

1 The steam life and service life data were determined by testing under controlled laboratory conditions up to the time indicated. Actual operating conditions may affect the filter's long term resistance to steam sterilization and hot air service. Filters should be qualified for each process application.

Maximum Forward Steaming Conditions

 
300 mbard (4.4 psid) differential pressure at 125oC  
 

Maximum Temperature and Differential Pressure 2

 
Maximum forward differential pressures in compatible fluids are:
 5.5 bard (80 psid) at 40oC
 3.0 bard (43 psid) at 80oC
 
2 In compatible fluids which do not soften, swell, or adversely affect the filters or its materials of construction

Forward Flow Intergrity Test Values3

 
With water wet cartridges and air as test gas < 50 mL/min at 2060 mbar (30 psi).
Preflush at 5 L/min per module for 10 minutes prior to Forward Flow testing
 

3Please contact Pall for multi-element integrity test values. Values are for one 254mm (10 inch) filter at 20oC.

Typical Liquid Flow Rates


 View additional Sterile Filtration and Bioburden Control products and technologies.

Application
Filters - Liquid - Bioburden Reduction (0.45 micron)