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HDC® II Filter Cartridges for Liquid Applications

Pall HDC® II all-polypropylene liquid filter cartridges incorporate proprietary HDC II tapered pore polypropylene depth media. The single open-ended (SOE) AB filter cartridge style features a high-area pleated modular element construction designed to fit in sanitary filter housings.

HDC IISOEliquidfilter cartridges are well-suited for a broad range of fine particle and prefiltration applications where purity, economy, and reliability are critical. Typical biopharmaceutical applications include biologicals, pharmaceuticals, fermentation feeds, and intermediates, and vaccines.

Features and Benefits

  • All-polypropylene construction
  • Resin-free, melt-sealed
  • Constant density tapered pores
  • High-capacity for long-life
  • Fixed pore, non-shedding
  • Low protein binding
  • Low extractables
  • Broad chemical compatibilities
  • Autoclavable and steamable in situ
  • Manufactured for use in conformance with cGMP
  • ISO 9000 Certified Quality System
  • Pharmaceutical P optimized grades with Certificate of Test provided
  • FDA-listed materials per 21 CFR

Note: These filters are also available in Kleenpak capsule format.

Quality and Bio-Safety Biological Tests

Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics

Effluent Quality Tests*

Meets Cleanliness per USP Particulates in Injectables
  • Non-Fiber-Releasing Non-Pyrogenic per USP
  • Bacterial Endotoxins (< 0.25 EU/mL)
  • Meets Total Organic Carbon and Water Conductivity per USP Purified Water, pH per USP Sterile Purified Water

* Per lot sample soak or rinse-up flush aliquots.

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Description

Pall HDC® II all-polypropylene liquid filter cartridges incorporate proprietary HDC II tapered pore polypropylene depth media. The single open-ended (SOE) AB filter cartridge style features a high-area pleated modular element construction designed to fit in sanitary filter housings.

HDC IISOEliquidfilter cartridges are well-suited for a broad range of fine particle and prefiltration applications where purity, economy, and reliability are critical. Typical biopharmaceutical applications include biologicals, pharmaceuticals, fermentation feeds, and intermediates, and vaccines.

Features and Benefits

  • All-polypropylene construction
  • Resin-free, melt-sealed
  • Constant density tapered pores
  • High-capacity for long-life
  • Fixed pore, non-shedding
  • Low protein binding
  • Low extractables
  • Broad chemical compatibilities
  • Autoclavable and steamable in situ
  • Manufactured for use in conformance with cGMP
  • ISO 9000 Certified Quality System
  • Pharmaceutical P optimized grades with Certificate of Test provided
  • FDA-listed materials per 21 CFR

Note: These filters are also available in Kleenpak capsule format.

Quality and Bio-Safety Biological Tests

Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics

Effluent Quality Tests*

Meets Cleanliness per USP Particulates in Injectables
  • Non-Fiber-Releasing Non-Pyrogenic per USP
  • Bacterial Endotoxins (< 0.25 EU/mL)
  • Meets Total Organic Carbon and Water Conductivity per USP Purified Water, pH per USP Sterile Purified Water

* Per lot sample soak or rinse-up flush aliquots.

Specifications

Materials of Construction

 
Medium  Polypropylene
Support and Drainage Layers  Polypropylene
Core,Cage and End Caps  Polypropylene
Adapter (P grade)  Polypropylene with polyetherimide reinforcing ring
 O-ring  Silicone1
 
1 Other polymers available on request

 

Removal Ratings (Liquid) 2

 
 40 µm, 20 µm, 10 µm, 6 µm, 4.5 µm, 2.5 µm, 1.2 µm, 0.6 µm 3
 
2 > 99.98% by modified OSU-F2 test. 0.6 to 20 µm in water, and 40 µm in oil.
3 Extrapolated value.

 

Nominal Dimensions

 
 Lengths  254 mm (10 in.),  508 mm (20 in.), 762 mm (30 in.), and 1016 mm (40 in.)
 Diameter  70 mm (2.75 in.)
 

 

Operating Conditions

 
 Maximum Differential Pressure and Temperature 4 

5.5 bard (80 psid) to 50 °C

4.1 bard (60 psid) to 80 °C
 
4  Using compatible fluids.

 

Autoclaving and Steaming In Situ5

 
 Maximum Steam Temperature  140 °C
 
5 Filters should be qualified in actual use. Contact Pall for recommended procedures.  

 

Typical Liquid Flow Rates6

HDC® II Filter Cartridges for Liquid Applications: Typical Liquid Flow Rates

HDC® II Filter Cartridges for Liquid Applications: Typical Liquid Flow Rates

6 Typical initial media ∆P 254mm (10 in.) element; water at 20 °C; viscosity 1 cP. For assistance in filter assembly sizing and housing selection, contact your local Pall representative.

Type

Filter Cartridges

Use

Bioburden Filtration

Product Summary

With a high capacity for long service life and broad chemical compatibilities, the HDC® II Liquid Filter Cartridges provides a high-quality SOE option for sanitary filter housings. Components are FDA listed and manufactured under ISO 9000 Quality System. It is melt sealed to ensure sterility for purification products. It has many applications, including biopharmaceuticals and vaccines.

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