Supor® EBV Sterilizing-Grade Filter Cartridges product photo Primary L

Supor® EBV Sterilizing-Grade Filter Cartridges

Supor® EBV polyethersulfone membrane cartridges are validated, 0.2 µm sterilizing-grade filters with a unique combination of Pall Ultipleat® filter construction and built-in prefiltration to give longer filter life and lower filtration costs. The filters are suitable for sterile filtration of a wide range of fluids including buffers, biological fluids, tissue culture media, ophthalmic products and many others. The low protein and preservative binding of the Supor polyethersulfone membranes also ensures maximum transmission of active ingredients.  

Pall’s AB style filters are disposable 254mm (10 inch) modular element cartridges assembled in 254, 508, 762 and 1016 mm lengths to be used with stainless steel housing assemblies, most suitable for medium to large scale manufacturing operations (100 L to >1000 L). With Code 7 fittings as standard, these are the most versatile filtration units in Pall’s range, and incorporate a broader range of filtration media than any other filter type. These filters, when encapsulated, become the Kleenpak™ Nova capsule format.
 

Key Features and Benefits

  • Hydrophilic polyethersulfone membrane for low adsorption and wide chemical compatibility
  • Patented Ultipleat® technology for high-area and good flow rates
  • Built-in prefilter layer for long-life and low filtration costs
  • High-strength construction tolerates up to 1 bard (14.5 psid) differential pressure during steam-in-place sterilization

Quality Standards

  • Manufactured for use in conformance with cGMP 
  • 100% integrity tested
  • ISO 9000 Certified Quality System
  • Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics
  • Every filter tested during manufacture. Test correlated to microbial retention
  • Certificate of Test provided includes:
    • Fabrication Integrity 
    • Bacterial Retention 
    • Materials of constructions
    • Effluent quality for cleanliness, TOC and Water Conductivity, pH and Pyrogens



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Description
Supor® EBV polyethersulfone membrane cartridges are validated, 0.2 µm sterilizing-grade filters with a unique combination of Pall Ultipleat® filter construction and built-in prefiltration to give longer filter life and lower filtration costs. The filters are suitable for sterile filtration of a wide range of fluids including buffers, biological fluids, tissue culture media, ophthalmic products and many others. The low protein and preservative binding of the Supor polyethersulfone membranes also ensures maximum transmission of active ingredients.  

Pall’s AB style filters are disposable 254mm (10 inch) modular element cartridges assembled in 254, 508, 762 and 1016 mm lengths to be used with stainless steel housing assemblies, most suitable for medium to large scale manufacturing operations (100 L to >1000 L). With Code 7 fittings as standard, these are the most versatile filtration units in Pall’s range, and incorporate a broader range of filtration media than any other filter type. These filters, when encapsulated, become the Kleenpak™ Nova capsule format.
 

Key Features and Benefits

  • Hydrophilic polyethersulfone membrane for low adsorption and wide chemical compatibility
  • Patented Ultipleat® technology for high-area and good flow rates
  • Built-in prefilter layer for long-life and low filtration costs
  • High-strength construction tolerates up to 1 bard (14.5 psid) differential pressure during steam-in-place sterilization

Quality Standards

  • Manufactured for use in conformance with cGMP 
  • 100% integrity tested
  • ISO 9000 Certified Quality System
  • Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics
  • Every filter tested during manufacture. Test correlated to microbial retention
  • Certificate of Test provided includes:
    • Fabrication Integrity 
    • Bacterial Retention 
    • Materials of constructions
    • Effluent quality for cleanliness, TOC and Water Conductivity, pH and Pyrogens

Specifications

Materials of Construction

 
 Membrane  Dual layer polyethersulfone (PES)
 Support and Drainage      Polypropylene
 Core, Cage and End caps      Polypropylene
 O-rings      Silicone elastomer
 Sealing Technology  Thermal bonding without adhesives
 

Operating Parameters1

 
 Maximum Operating Pressure (Forward Direction)

5.5 bar (80 psi) @ 50 °C

3.0 bar (43.5 psi) @ 80 °C

 Maximum Operating Pressure (Reverse Direction) 2.0 bar (30 psi) @ 50 °C
 

1In compatible fluids which do not soften, swell, or adversely affect the filter or its materials of construction.

Sterilization2

 
 
Autoclave 5 x 60-minutes cycles at 125 °C
 In situ Steam     5 x 60-minutes cycles at 125 °C
 
2Maximum differential pressure during steam-sterilization is 1 bar (14.5 psi).

 

Nominal Dimensions

 
 Lengths  254 mm (10 in.), 508 mm (20 in.), 762 mm (30 in.), 1016 mm (40 in.)
 Diameter  70 mm (2.75 in.)
 

Extractables3

 
 Typical Extractables per 254mm (10 in.) Module  < 25 mg in water at 20 °C (68 °F) after 4 hours extraction
 

3 Tested on elements without pre-flushing.

Filter Area

 

 
 Nominal Filtration Area per 254mm (10 in.) Module  0.66 m2 (7.1 ft2)
 

 

Integrity Test Values for 254 mm (10 in.) Filter at 20 °C

 
 
 Maximum Allowable Forward Flow (Air Test Gas)  Water wet < 23 mL/min at 2760 mbar (40 psi)
 
Contact Pall for multi-element integrity test values and recommended test procedures.

 

Typical Liquid Flow Rates

Application
Filters - Liquid - Sterile (0.2 micron)
Segment
Filtration