Supor® EKV Membrane in Junior Filter Cartridges (MCY Style) product photo Primary L

Supor® EKV Membrane in Junior Filter Cartridges (MCY Style)

The Supor® EKV liquid single-use filter cartridge is a 0.2 micron rated, validated sterilizing grade membrane. It utilizes a laid-over-pleat membrane geometry for high flow rates and throughput performance; designed for the most cost-effective filtration of a wide range of liquids such as buffers, tissue culture media, and others. A PES membrane ensures very high compatibility over the whole pH range plus very low protein binding to ensure the maximum transmission of active ingredients.

Junior filter cartridges (MCY style) are liquid single-use filter cartridges for use with in-line stainless steel filter housings. They feature double O-ring piston seals comparable to ‘AB-style’ cartridges. They are designed to process volumes of material (30 L to 500 L) in a small-to-mid-size GMP manufacturing environment.

A validation package for Supor grade EKV filters supports the assurance of safety within your process.

Key Features and Benefits
  • Hydrophilic polyethersulfone membrane for low adsorption and wide chemical compatibility
  • Good wettability for a reliable integrity test
  • Patented Ultipleat® technology for high-area and good flow rates
  • Built-in, MachV asymmetric prefilter layer for long-life and low filtration costs
  • High-strength construction tolerates up to 1 bard (14.5 psid) differential pressure during steam-in-place sterilization

Quality Standards
  • Manufactured for use in conformance with cGMP
  • 100% integrity tested
  • ISO 9000 Certified Quality System
  • Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics
  • Every filter tested during manufacture. Test correlated to microbial retention.
  • Certificate of Test provided includes:
    • Fabrication Integrity
    • Bacterial Retention
    • Materials of constructions
    • Effluent quality for cleanliness, TOC and Water Conductivity, pH and Pyrogens


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Description

The Supor® EKV liquid single-use filter cartridge is a 0.2 micron rated, validated sterilizing grade membrane. It utilizes a laid-over-pleat membrane geometry for high flow rates and throughput performance; designed for the most cost-effective filtration of a wide range of liquids such as buffers, tissue culture media, and others. A PES membrane ensures very high compatibility over the whole pH range plus very low protein binding to ensure the maximum transmission of active ingredients.

Junior filter cartridges (MCY style) are liquid single-use filter cartridges for use with in-line stainless steel filter housings. They feature double O-ring piston seals comparable to ‘AB-style’ cartridges. They are designed to process volumes of material (30 L to 500 L) in a small-to-mid-size GMP manufacturing environment.

A validation package for Supor grade EKV filters supports the assurance of safety within your process.

Key Features and Benefits
  • Hydrophilic polyethersulfone membrane for low adsorption and wide chemical compatibility
  • Good wettability for a reliable integrity test
  • Patented Ultipleat® technology for high-area and good flow rates
  • Built-in, MachV asymmetric prefilter layer for long-life and low filtration costs
  • High-strength construction tolerates up to 1 bard (14.5 psid) differential pressure during steam-in-place sterilization

Quality Standards
  • Manufactured for use in conformance with cGMP
  • 100% integrity tested
  • ISO 9000 Certified Quality System
  • Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics
  • Every filter tested during manufacture. Test correlated to microbial retention.
  • Certificate of Test provided includes:
    • Fabrication Integrity
    • Bacterial Retention
    • Materials of constructions
    • Effluent quality for cleanliness, TOC and Water Conductivity, pH and Pyrogens

Specifications

Materials of Construction

 
Filter Membrane Hydrophilic PES
Support/Drainage Polypropylene
End Cap, Core and Cage Polypropylene
Sealing Technology Thermal bonding without adhesives
O-rings Silicone Elastomer
 

Operating Parameters1

 
Maximum Differential
Pressure
5.2 bar (75 psi) at 40°C
 
1 In compatible fluids which do not soften, swell or adversely affect the filter or its materials of construction

Sterilization2

 
Autoclave 5 x 60 minutes at 125°C, slow exhaust
In Situ Steam 30 x 60 minutes at 125°C
 
2 Water wet Supor EKV capsules prior to steaming to retain full water wettability for integrity testing

Typical Liquid Flow vs. Differential Pressure




Typical Extractables in Water at 20°C: < 10 mg per filter
Nominal Effective Filter Area (EFA): 1500 cm2 (1.6 ft2)

Type

Filter Cartridges

Use

Sterilizing-Grade Liquid Filtration

Ordering Information

 
Item Part Number
Supor® EKV Membrane in Junior Filter Cartridge style (MCY 4440)
Single open-ended cartridge, double external o-rings (silicone elastomer) and locating lugs
MCY4440EKVPH4
 

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