Microza* Membranes - Polyacrylonitrile product photo Primary L

Microza* Membranes - Polyacrylonitrile

Polymeric Membrane Morphology

Microza* ultrafiltration membranes are unique in their construction. Every membrane has an asymmetric structure,with a membrane layer both on the inside, and on the outside of the fiber, overlaying a core comprising a very open support for excellent flow characteristics, and a central strengthening layer for outstanding fiber durability in long-term service. Microza ultrafiltration membranes are resistant to flow in both directions, so there is no risk of delamination or membrane rupture during accidental back-pressure. In fact, in many installations, backpulsing can be used to maintain flux during extended run times.

Microza micofiltration membranes have smooth inner and outer membrane skins with a highly porous symmetrical support structure giving high-flow rates. These modules can also be backflushed.

All Microza membranes have surfaces that minimize entrapment and facilitate cleaning. All Microza membranes are manufactured in a single step, and are not composed of laminates. Membranes and modules are subjected to rigorous quality control to ensure consistency of performance, durability in service, and module integrity for the most demanding applications.

Polyacrylonitrile (PAN)

PAN membranes are ideally suited to bulk process applications, such as the purification of enzymes. They exhibit high-strength, coupled with high flux rates, minimizing installation size. PAN has a low fouling characteristic for these applications, simplifying cleaning.

The AP and AV series of Microza hollow fiber ultrafiltration modules feature unique double-skinned proprietary polyacrylonitrile (PAN) membranes with dense internal layer. Available in 6,000, 13,000, 50,000 and 80,000 molecular weight cut-offs, the modules are used in a range of pharmaceutical applications especially in purification and processing of aqueous enzymes and protein solutions. 80,000 MWCO modules are especially useful for raw water pretreatment to pharmaceutical water purification plant.

Key Features 

  • Hydrophilic polyacrylonitrile membrane provides low fouling and excellent flux recovery
  •  Combination of high-strength and high-capacity due to unique membrane construction
  • High-strength fiber allows reverse filtration to assist cleaning in difficult applications
  • Available in a range of sizes from 0.012 m2 (0.13 ft2) to more than 40 m2 (425 ft2)
  • Compatible for continuous operation up to 50 °C (122 °F)
  • Easily cleanable in most biological applications using minimum chemicals or detergents
  • Meets the specifications for biological tests listed in the current revision of USP for class VI plastics at 121 °C (249 °F)
  • LGV and LOV modules especially optimized for raw water duty 
  • pH 2 -10

Microza Module Types

Microza hollow fiber modules are available with housings made from polysulfone (native, clear), filled polysulfone (white, opaque), and polyvinylchloride (PVC). Polysulfone modules will withstand autoclaving and in some cases steaming. Clear polysulfone modules are recommended for more critical pharmaceutical applications. Filled polysulfone and PVC modules are ideally suited to long term installations where light might cause biofilm to form, or for bulk processes involving light sensitive materials. PVC modules are idea for use in feed water systems and bulk processes.

Microza modules are available with industry standard clamp fittings on the feed and retentate side, and some with quick connects. All steamable modules designed for long term use in critical applications such as perfusion have sanitary clamp connections on the feed/retentate and filtrate sides, or filtrate hose barbs on laboratory scale modules.

Retrofitting Existing Applications

To retrofit an existing application,membrane rating should be chosen to be equivalent or superior in performance. For ultrafiltration membranes, this may require testing more than a single cut-off. Differences in membrane area and lumen diameter can typically be accommodated by adjustments to operating conditions to ensure that trans-membrane pressure and fluid velocity conditions at the membrane surface are similar. Hollow fiber modules can be joined end-to-end as required to create similar path length systems. Small adjustments to physical dimensions, and differences in connection type are accomplished using adapters. Please contact Pall for assistance with selecting the right modules to retrofit an existing installation.

* Microza is a trademark of Asahi Kasei Corporation



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Description

Polymeric Membrane Morphology

Microza* ultrafiltration membranes are unique in their construction. Every membrane has an asymmetric structure,with a membrane layer both on the inside, and on the outside of the fiber, overlaying a core comprising a very open support for excellent flow characteristics, and a central strengthening layer for outstanding fiber durability in long-term service. Microza ultrafiltration membranes are resistant to flow in both directions, so there is no risk of delamination or membrane rupture during accidental back-pressure. In fact, in many installations, backpulsing can be used to maintain flux during extended run times.

Microza micofiltration membranes have smooth inner and outer membrane skins with a highly porous symmetrical support structure giving high-flow rates. These modules can also be backflushed.

All Microza membranes have surfaces that minimize entrapment and facilitate cleaning. All Microza membranes are manufactured in a single step, and are not composed of laminates. Membranes and modules are subjected to rigorous quality control to ensure consistency of performance, durability in service, and module integrity for the most demanding applications.

Polyacrylonitrile (PAN)

PAN membranes are ideally suited to bulk process applications, such as the purification of enzymes. They exhibit high-strength, coupled with high flux rates, minimizing installation size. PAN has a low fouling characteristic for these applications, simplifying cleaning.

The AP and AV series of Microza hollow fiber ultrafiltration modules feature unique double-skinned proprietary polyacrylonitrile (PAN) membranes with dense internal layer. Available in 6,000, 13,000, 50,000 and 80,000 molecular weight cut-offs, the modules are used in a range of pharmaceutical applications especially in purification and processing of aqueous enzymes and protein solutions. 80,000 MWCO modules are especially useful for raw water pretreatment to pharmaceutical water purification plant.

Key Features 

  • Hydrophilic polyacrylonitrile membrane provides low fouling and excellent flux recovery
  •  Combination of high-strength and high-capacity due to unique membrane construction
  • High-strength fiber allows reverse filtration to assist cleaning in difficult applications
  • Available in a range of sizes from 0.012 m2 (0.13 ft2) to more than 40 m2 (425 ft2)
  • Compatible for continuous operation up to 50 °C (122 °F)
  • Easily cleanable in most biological applications using minimum chemicals or detergents
  • Meets the specifications for biological tests listed in the current revision of USP for class VI plastics at 121 °C (249 °F)
  • LGV and LOV modules especially optimized for raw water duty 
  • pH 2 -10

Microza Module Types

Microza hollow fiber modules are available with housings made from polysulfone (native, clear), filled polysulfone (white, opaque), and polyvinylchloride (PVC). Polysulfone modules will withstand autoclaving and in some cases steaming. Clear polysulfone modules are recommended for more critical pharmaceutical applications. Filled polysulfone and PVC modules are ideally suited to long term installations where light might cause biofilm to form, or for bulk processes involving light sensitive materials. PVC modules are idea for use in feed water systems and bulk processes.

Microza modules are available with industry standard clamp fittings on the feed and retentate side, and some with quick connects. All steamable modules designed for long term use in critical applications such as perfusion have sanitary clamp connections on the feed/retentate and filtrate sides, or filtrate hose barbs on laboratory scale modules.

Retrofitting Existing Applications

To retrofit an existing application,membrane rating should be chosen to be equivalent or superior in performance. For ultrafiltration membranes, this may require testing more than a single cut-off. Differences in membrane area and lumen diameter can typically be accommodated by adjustments to operating conditions to ensure that trans-membrane pressure and fluid velocity conditions at the membrane surface are similar. Hollow fiber modules can be joined end-to-end as required to create similar path length systems. Small adjustments to physical dimensions, and differences in connection type are accomplished using adapters. Please contact Pall for assistance with selecting the right modules to retrofit an existing installation.

* Microza is a trademark of Asahi Kasei Corporation

Specifications

Materials of Construction

 
Membrane Polyacrylonitrile
Housing Native clear polysulfone (P) or PVC (V)
Potting Material Epoxy Resin
Gasket Silicone (P) or butyl rubber (NBR) (V)
Bacteriostat Glycerin 65%, Ethanol 2%, water balance
 

 

Connectors and Adapters

 
A - A1 Small hose barb 4.5 mm (3/16 in.)
A2 Small hose barb 6 mm (¼ in)
B - B1

Quick connect -To convert feed/retentate to:
1½ in. sanitary clamp, order part number 0450163 (fits in body of module)
¼ in. sanitary clamp, order part number 2055675 (fits in body of module)
¼ in. hosebarb (fits on quick-connect) order part number 2055999 (polypropylene)
¼ in. FNPT (fits on quick-connect) order part number 2089150 (316L stainless steel)

C - C3 1 in. sanitary flange (ferrule face 34 mm [1.34 in.]) 
C4 1½ in. sanitary flange (ferrule face 50 mm [1.98 in.]) 
C5 2 in. sanitary flange (ferrule face 64 mm [2.52 in.])  
C7 4 in. sanitary flange (ferrule face 117 mm [4.61 in.])  
C8 6 in. sanitary flange (ferrule face 157 mm [6.18 in.])  
D - D2 Cap nut, 38.5 mm diameter
D3 Cap nut, 48.5 mm diameter
 

 

Part Numbers and Technical Specification - Table 1 1

 
Part Number Rating
(MWCO, Daltons)
Fiber ID/OD (mm) Nominal Length (2)
(mm)
Membrane Area
(m2)
Clean Water Flux
Lh-1 bar, 25 oC
Crossflow Rate for 1ms-1 fluid velocity
AIP-0013 6000 0.8 / 1.4 mm  130 0.017  0.8 181
AIP-1010 6000 0.8 / 1.4 mm 347 0.19 10 724
AIP-2013 6000 0.8 / 1.4 mm  552 1.0 50 1629
AIP-3013 6000 0.8 / 1.4 mm 1129 4.7 160 3655
AIV-3010 6000 0.8 / 1.4 mm 1126 4.7 170 3655
AIV-5010 6000 0.8 / 1.4 mm 1126 12.3 700 10134
ACP-0013 13000 0.8 / 1.4 mm 130 0.017 2.6 181
ACP-0053 13000 1.4 / 2.3 mm 130 0.012 1.6 222
ACP-1010 13000 0.8 / 1.4 mm 347 0.19 34 724
ACP-1050 13000 1.4 / 2.3 mm 347 0.12 19 776
ACP-2013 13000 0.8 / 1.4 mm 552 1.0 160 1629
ACP-2053 13000 1.4 / 2.3 mm 552 0.6 90 1773
ACP-3013 13000 0.8 / 1.4 mm 1129 4.7 750 3655
ACP-3053 13000 1.4 / 2.3 mm 1129 3.1 360 3990
ACV-3010 13000 0.8 / 1.4 mm 1126 4.7 830 3655
ACV-3050 13000 1.4 / 2.3 mm  1126 3.1 420 3990
ACV-5010 13000 0.8 / 1.4 mm 1126 12.3 2200 10134
ACV-5050  13000 1.4 / 2.3 mm 1126 7.8 1100 11084
LGV-3010  13000 0.8 / 1.4 mm 1126 7.6 500 3257
LGV-5210  13000 0.8 / 1.4 mm 2227 41 4000 8686
AHP-0013  50000 0.8 / 1.4 mm 130 0.017 7.6 181
AHP-1010  50000 0.8 / 1.4 mm 347 0.19 82 724
AHP-2013  50000 0.8 / 1.4 mm 552 1.0 460 1629
AHP-3013  50000 0.8 / 1.4 mm 1129 4.7 2250 3655
AHV-3010  50000 0.8 / 1.4 mm 1126 4.7 2500 3655
LOV-3010  80000 0.8 / 1.4 mm 1126 7.6 1500 3257
LOV-5210  80000 0.8 / 1.4 mm  2227 41 7000 8686
 

 

Part Numbers and Technical Specification - Table 2 1

 
Part Number Maximum Pressure Feed/TMP/Permeate at 50 oC (barg) Volume Feed Side (3) (mL) Volume Permeate Side (3)  (mL) Feed/Retentate Connection Permeate Connection
AIP-0013  1/1/1 9 9 A2 A1
AIP-1010 2/3/2 90 120 B1 B1
AIP-2013 5/3/3 300 500 C4 C3
AIP-3013 5/3/3 1200 2700 C5 C4
AIV-3010 3/3/3 1200 2700 C7 D2
AIV-5010 3/3/3 3800 5300 C8 D3
ACP-0013 1/1/1 9 9 A2 A1
ACP-0053 1/1/1 10 9 A2 A1
ACP-1010 2/3/3 90 120 B1 B1
ACP-1050 3/3/3 90 120 B1 B1
ACP-2013 5/3/3 300 500 C4 C3
ACP-2053 5/3/3 310 500 C4 C3
ACP-3013 5/3/3 1200 2700 C5 C4
ACP-3053 5/3/3 1200 2850 C5 C4
ACV-3010 3/3/3 1200 2700 C7 D2
ACV-3050 3/3/3 1200 2700 C7 D2
ACV-5010 3/3/3 3800 5300 C8 D3
ACV-5050 3/3/3 3800 5300 C8 D3
LGV-3010 3/3/3 - - C7/D2 C7
LGV-5210 3/3/3 - - C8/D3 C8
AHP-0013 1/1/1 9 9 A2 A1
AHP-1010 2/2/2 90 120 B1 B1
AHP-2013 4/2/2 300 500 C4 C3
AHP-3013 4/2/2 1200 2700 C5 C4
AHV-3010 3/2/2 1200 2700 C7 D2
LOV-3010 <span
Ordering Information
For ordering information, please see tables under 'Specifications' tab.
Application
Membranes
Segment
Tangential Flow Filtration