Pall Microdisc Capsules with Pegasus™ Protect Virus Prefilter Membrane product photo Primary L

Pall Microdisc Capsules with Pegasus™ Protect Virus Prefilter Membrane

Protecting Critical Virus Filtration

Pegasus Protect virus prefiltration combines with Pegasus Prime virus filtration to deliver the first gamma-sterilized pre-filter & virus filter combination. Together, these simplify process development, validation and operations while saving time and delivering improved process economy.

Process developers can quickly deliver a robust, scalable virus filtration process using a minimum of sample volume, and be confident of successful virus validation. This choice supports clinical manufacturing with a solution that is easy to use and versatile to work alone or with integrated and automated single-use systems.

Both gamma irradiated and non-irradiated Microdisc capsules containing Pegasus Protect media are optimized for the confirmation and validation of performance at a small scale using minimal volumes of process fluid.

Performance established during small scale trials can be easily scaled as both Pegasus Protect prefilters and Pegasus Prime virus filters are available in a range of optimized capsule and filter formats which maintain a constant area ratio between prefiltration and virus filtration at all scales.

All process scale devices can be integrated into single-use and automated solutions to offer the highest degree of control, flexibility and security.

Features and Benefits

 
Removes filter plugging substances virus filters Reduce plugging of Pegasus Prime
  • Smaller virus filter sizing
  • Minimized cost of goods.
  • Shorter processing times
  • Increased robustness to natural process fluid variation
The scale-up range provides a consistent prefilter to virus filter area ratio at all scales Consistent performance
  • Controlling scaling risks
  • Faster, simple scale-up and viral validation
Fully disposable capsule with Luer connections Easy-to-use, ready-to-use
 


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Pegasus™ Protect membrane in Microdisc capsules, 0.2 µm nominal pore size (adsorptive pre-filter), 3.9 cm² EFA, suitable for gamma irradiation, box of 4

Product ID: 4MCFPRT4
Unit of Measure
1/PAC
Min Order Qty
1
Membrane Material
Nylon
Industry-Specific Certification
Pharmaceutical (Scaling Tool)
Effective Filtration Area (Metric)
3.9 cm²
Format
Microdisc
Inlet Connection
Female luer lock
Outlet Connection
Male luer slip
See All Attributes
$ 119.18

Pegasus™ Protect membrane in Microdisc capsules, 0.2 µm nominal pore size (adsorptive pre-filter), 3.9 cm² EFA, suitable for gamma irradiation, box of 12

Product ID: 4MCFPRT12
Unit of Measure
1/PAC
Min Order Qty
1
Membrane Material
Nylon
Industry-Specific Certification
Pharmaceutical (Scaling Tool)
Effective Filtration Area (Metric)
3.9 cm²
Format
Microdisc
Inlet Connection
Female luer lock
Outlet Connection
Male luer slip
See All Attributes
$ 323.20

Pegasus™ Protect membrane in Microdisc capsules, 0.2 µm nominal pore size (adsorptive pre-filter), 3.9 cm² EFA, gamma irradiated, box of 12

Product ID: 4MCFPRT12R
Unit of Measure
1/PAC
Min Order Qty
1
Membrane Material
Nylon
Industry-Specific Certification
Pharmaceutical (Scaling Tool)
Effective Filtration Area (Metric)
3.9 cm²
Format
Microdisc
Inlet Connection
Female luer lock
Outlet Connection
Male luer slip
See All Attributes
$ 296.37

Pegasus™ Protect membrane in Microdisc capsules, 0.2 µm nominal pore size (adsorptive pre-filter), 3.9 cm² EFA, gamma irradiated, box of 4

Product ID: 4MCFPRT4R
Unit of Measure
1/PAC
Min Order Qty
1
Membrane Material
Nylon
Industry-Specific Certification
Pharmaceutical (Scaling Tool)
Effective Filtration Area (Metric)
3.9 cm²
Format
Microdisc
Inlet Connection
Female luer lock
Outlet Connection
Male luer slip
See All Attributes
$ 108.78
Description

Protecting Critical Virus Filtration

Pegasus Protect virus prefiltration combines with Pegasus Prime virus filtration to deliver the first gamma-sterilized pre-filter & virus filter combination. Together, these simplify process development, validation and operations while saving time and delivering improved process economy.

Process developers can quickly deliver a robust, scalable virus filtration process using a minimum of sample volume, and be confident of successful virus validation. This choice supports clinical manufacturing with a solution that is easy to use and versatile to work alone or with integrated and automated single-use systems.

Both gamma irradiated and non-irradiated Microdisc capsules containing Pegasus Protect media are optimized for the confirmation and validation of performance at a small scale using minimal volumes of process fluid.

Performance established during small scale trials can be easily scaled as both Pegasus Protect prefilters and Pegasus Prime virus filters are available in a range of optimized capsule and filter formats which maintain a constant area ratio between prefiltration and virus filtration at all scales.

All process scale devices can be integrated into single-use and automated solutions to offer the highest degree of control, flexibility and security.

Features and Benefits

 
Removes filter plugging substances virus filters Reduce plugging of Pegasus Prime
  • Smaller virus filter sizing
  • Minimized cost of goods.
  • Shorter processing times
  • Increased robustness to natural process fluid variation
The scale-up range provides a consistent prefilter to virus filter area ratio at all scales Consistent performance
  • Controlling scaling risks
  • Faster, simple scale-up and viral validation
Fully disposable capsule with Luer connections Easy-to-use, ready-to-use
 
Specifications
Materials of Construction
Filter Membrane: Nylon
Housing, Vent Plug and Support: Polypropylene

Retention Ratings
Pore size : 0.2 μm nominal

Effective Filter Area (EFA) (Nominal)
3.9 cm2

Operating Parameters
Maximum Temperature: 40 °C
Maximum Pressure: 3.1bar (45 psi)*
Maximum Differential Pressure: 3.1 bar (45 psi)*
*up to 12 hours at 25 °C; up to 6 hours at 40 °C

Recommended Operating Conditions
35 mbard (0.5 psid) or 2 mL/min water at 20 °C*
*when used with Pegasus Prime Microdisc capsules

Typical Hold-Up Volume (with air purge)
< 125 μL

Dimensions (Nominal)
Length: 2.0 cm (0.8 in.)
Diameter : 3.0 cm (1.2 in.)

Connection Type
Female Luer-Lock inlet, male slip Luer outlet
Performance
Figure 1
Impact of Pegasus Protect Prefiltration on Required Virus Flters Per Batch

Scalable Solutions

Prefiltration area and flowrate are critical variables that may affect the performance of Pegasus Protect prefiltration and Pegasus Prime virus removal filters when used in combination.

To control these variables Pegasus Protect prefiltration media is available in a range of formats, designed to maintain a consistent pre-filter to virus-filter ratio. This control ensures predictable and consistent performance at all scales from the initial Microdisc scale trials to clinical manufacturing.

 
  Area Microdisc Capsules Area Kleenpak / Mini
Kleenpak Capsules
Pegasus Protect Prefiltration 3.9 cm2 286 cm2
Pegasus Prime Virus Filter 2.8 cm2 204 cm2
Area ratio 1.4 : 1 1.4 : 1
 
Ordering Information

Ordering Information

 
Part Number Description Pkg
4MCFPRT4 Pall Microdisc Capsules with Pegasus Protect Filter Membrane 4/box
4MCFPRT12 Pall Microdisc Capsules with Pegasus Protect Filter Membrane 12/box
(4 x 3 lots)
4MCFPRT4R Pall Microdisc Capsules with Pegasus Protect Filter Membrane - Gamma irradiated 4/box
4MCFPRT12R Pall Microdisc Capsules with Pegasus Protect Filter Membrane - Gamma irradiated 12/box
(4 x 3 lots)