Ultipor® VF Grade DV20 Virus Removal Filter Membrane in Minidisc Capsules  product photo Primary L

UltiporĀ® VF Grade DV20 Virus Removal Filter Membrane in Minidisc Capsules

Minidisc filter capsules incorporate Ultipor® VF Grade DV20 membrane and are validated for virus removal.

They are also suitable for small-scale membrane qualification studies such as bacteriophage or prion (TSE agent) clearance, as well as membrane flow rate, capacity and protein transmission studies. Every filter is identified by a lot number and a unique serial number for complete traceability of manufacturing history and for user’s traceability system and manufactured under a Quality Management System certified to ISO 9001:2008.

Key Features

  • Incorporates Ultipor VF Grade DV20 virus removal filter membrane
  • Identical membrane to larger virus cartridges
  • Fully disposable capsule with Luer-Lok* connections
  • Individual capsules identified by lot and serial number
  • 100% manufacturing assembly tested
  • Membrane bacteriophage tested
  • Pre- and post-installation tested
  • Low protein-binding
  • Robust membrane with high viral clearance and resistance to plugging

Benefits

  • Robust, high viral clearance
  • Reliable scalability
  • Easy handling, ready to use
  • Easy identification of individual capsules with complete traceability of manufacturing history
  • Assurance of consistently high quality at point of use
  • Flow decay minimized at high virus spike concentrations and with more complex or concentrated feeds

High Quality Standards

Meets the current USP requirements under Section <85> Bacterial Endotoxins Test

Materials

Filter fluid path components have met the specifications under Section <88> Biological Reactivity Tests in vivo listed in the current revision of the United States Pharmacopeia (USP) for Class VI plastics at 121°C.


* Required
Description
Minidisc filter capsules incorporate Ultipor® VF Grade DV20 membrane and are validated for virus removal.

They are also suitable for small-scale membrane qualification studies such as bacteriophage or prion (TSE agent) clearance, as well as membrane flow rate, capacity and protein transmission studies. Every filter is identified by a lot number and a unique serial number for complete traceability of manufacturing history and for user’s traceability system and manufactured under a Quality Management System certified to ISO 9001:2008.

Key Features

  • Incorporates Ultipor VF Grade DV20 virus removal filter membrane
  • Identical membrane to larger virus cartridges
  • Fully disposable capsule with Luer-Lok* connections
  • Individual capsules identified by lot and serial number
  • 100% manufacturing assembly tested
  • Membrane bacteriophage tested
  • Pre- and post-installation tested
  • Low protein-binding
  • Robust membrane with high viral clearance and resistance to plugging

Benefits

  • Robust, high viral clearance
  • Reliable scalability
  • Easy handling, ready to use
  • Easy identification of individual capsules with complete traceability of manufacturing history
  • Assurance of consistently high quality at point of use
  • Flow decay minimized at high virus spike concentrations and with more complex or concentrated feeds

High Quality Standards

Meets the current USP requirements under Section <85> Bacterial Endotoxins Test

Materials

Filter fluid path components have met the specifications under Section <88> Biological Reactivity Tests in vivo listed in the current revision of the United States Pharmacopeia (USP) for Class VI plastics at 121°C.
Applications
  • Virus removal and small-scale membrane qualification studies such as bacteriophage or prion (TSE agent) clearance
  • Membrane flow rate studies
  • Capacity studies
  • Protein transmission studies
Specifications

Materials of Construction

 
Item Material
Membrane Hydrophilic modified polyvinylidene fluoride (PVDF)
Support Disc Polypropylene (Non-woven)
O-ring EPDM
Capsule Inlet and Outlet Polycarbonate
 

Removal Rating

 
Item Removal
Small viruses > 3 log TR*†
Large viruses > 6 log TR **
 
* Claims based on challenge with parovirus model bacteriophage (bacterial virus) PP7
** Claims based on challenge with parovirus model bacteriophage (bacterial virus) PR772
† > 4 LRV for PP7 bacteriophage per Parenteral Drug Association (PDA) TR 41 rating method for small virus-retentive filters. > 4 LRV typically with mammalian parvoviruses


Effective Surface Area

 
9.6 cm² (1.49 in²) 
 

Operating Parameters²

 
Maximum Temperature  25 °C
Maximum Operating Pressure 3.1 barg (45 psig)
Maximum Differential Pressure 3.1 barg (45 psig)
 
² Using compatible liquids. Maximum air/gas pressure for installation test 3.4 bar g (50 psi)
Performance

Typical Flow vs. Differential Pressure


Typical Clean Water Flow at Ambient Conditions



Ordering Information
 
Description Part Number*
Minidisc Capsules with Ultipor® VF Grade DV20 Membrane 10MCFDV20
 
* Capsules are supplied in boxes of 3

Equipment Required for Laboratory Testing

 
Pressure Vessels Part Number
Junior-style vessel BLS7001G23J
Sealkleen vessel ZLK702G23LHKH4
Novasip™ vessel C3EP1
 

 
Accessories (Novasip Vessel) Part Number
Adapter 1 in. TC/Male Stäubli connector plug (3 mm) R ¼ in. GFX0290
TC clamp + silicone gasket SLK1TC23H4
 

 
Accessories (Junior, Sealkleen Vessels) Part Number
Adapter 1 in. TC/Male Stäubli connector plug (3 mm) R ¼ in. GFX0290
Male Stäubli connector plug (3 mm) R ¼ in. GFX0235
 
Application
Filters - Specialist
Segment
Viral Clearance