Compact, Easily-scalable Filter Discs for Virus Removal and Small-scale Membrane Qualification Studies

Pegasus SV4 Virus Removal filters combine robust, high viral clearance of parvovirus and larger viruses with high throughput capacity and stable flowrates, in both dilute and complex concentrated biological fluids. Consistent flowrates and throughput performance provide superior control of process costs and maximizes virus filtration economy and efficiency.

Pegasus SV4 Virus Removal Membrane Filter Discs are purpose-designed for small-scale membrane qualification studies such as bacteriophage or prion (TSE agent) clearance, as well as membrane flow rate, capacity and protein transmission studies. Filter discs are lot sample tested and manufactured under a Quality Management System certified to ISO 9001:2008 in order to assure consistently high quality.

Features	Benefits
Pegasus SV4 virus removal filter membrane	Robust, high > 4 LRV parvovirus clearance
Constant flow and high throughput performance	Maximize virus filter process economy and efficiency
Identical membrane to larger production scale Pegasus SV4 virus filter cartridges	Offers reliable scalability
Used in Pall FTK-200 disc holder	Easy handling
Individual membrane box identified by lot number	Complete traceability of manufacturing history
Manufacturing lot sample tested	Assurance of consistently high quality
Membrane bacteriophage tested	Assurance of consistently high quality
Pre- and post-use installation testable	Assurance of consistently high quality at point of use
Low protein-binding	High protein recovery
Robust membrane with high viral clearance and resistance to plugging	Flow decay minimized at high virus spike concentrations and with complex or concentrated feeds

Materials

• Filter fluid path components have met the specifications under Section <88> Biological Reactivity Tests in vivo listed in the current revision of the United States Pharmacopeia (USP) for Class VI plastics at 121 °C.