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AcroPak™ 400, 800, and 1500 Capsules With Supor® EKV Membrane
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AcroPak 1500 Capsules With Supor EKV Membrane
AcroPak 400 Capsules With Supor EKV Membrane
AcroPak 800 Capsules With Supor EKV Membrane
Description
For Cost-Effective Filtration of Buffers, Tissue Culture Media, and Other Biological Solutions
- Newer technology recommended for simplified scale-up
- Disposable design reduces labor costs associated with assembling, cleaning, and testing stainless steel filter holders
- Encapsulated format for ease of use
- Extended life with built-in MachV asymmetric prefilter layer for maximum flow and throughput performance
- Low adsorption and high chemical compatibility with hydrophilic polyethersulfone membrane for high compatibility over the entire pH range and low protein binding
- Gamma-irradiated, non-pyrogenic, and non-cytotoxic
- Inherently hydrophilic for reliable integrity testing
Video: Using an AcroPak Filter With a Peristaltic Pump
Applications
- Suitable for sterile filtration of a wide range of fluids, including:
- Buffers
- Biological fluids
- Cell culture media
- Ophthalmic products
Specifications
Materials of Construction
- Filter Media: Supor EKV [hydrophilic polyethersulfone (PES)] membrane
- Housing, Vent Plug, and Support Material: Polypropylene
- Filling Bell: Polycarbonate (no filling bell on sanitary flange option)
- Sealing Technology: Thermal bonding without adhesives
Pore Size
- 0.2 μm
Effective Filtration Area
- 400 Series: 375 cm2
- 800 Series: 750 cm2
- 1500 Series: 1500 cm2
Dimensions
- Housing Diameter (including valves): 9.4 cm (3.7 in.)
- 400 Series Housing Length:
12460: 11.7 cm (4.6 in.)
12461: 15.7 cm (6.2 in.) - 800 Series Housing Length:
12463: 15.7 cm (6.2 in.)
12464: 19.7 cm (7.7 in.) - 1500 Series Housing Length:
12466: 17.4 cm (6.8 in.)
12467: 21.0 cm (8.3 in.)
Inlet/Outlet Connections
- 400 Series
12460: 25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection
12461: 13 mm (1/2 in.) hose barb inlet/outlet connection - 800 Series
12463: 25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection
12464: 13 mm (1/2 in.) hose barb inlet/outlet connection - 1500 Series
12466: 25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection
12467: 13 mm (1/2 in.) hose barb inlet/outlet connection
Maximum Operating Temperature
- 40 ºC (104 ºF) at 4.0 bar (400 kPa, 58 psi)
Maximum Operating Pressure
- 5.2 bar (520 kPa, 75 psi) at 20 ºC (68 ºF)
Recommended Integrity Test Minimum Bubble Point - Water
- 3.32 bar (332 kPa, 48 psi) Typical Water Flow Rate
Typical Water Flow Rate
- 400 Series: 700 mL/min/0.1 bar (483 mL/min/psi)
- 800 Series: 1.5 L/min/0.1 bar (1.0 L/min/psi)
- 1500 Series: 3.2 L/min/0.1 bar (2.2 L/min/psi)
Bacterial Retention
- Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision
Endotoxin Level
- < 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
- Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
- Sterilized by gamma irradiation and individually packaged
Type
Filter Capsules
Application
Sterile Filtration
Product Summary
For cost-effective filtration of buffers, tissue culture media, and other biological solutions. Disposable design reduces labor costs associated with assembling, cleaning, and testing stainless steel filter holders.
