Filter Plates

By combining innovative membrane filter technology with optimized multi-well filter plate designs, Pall’s AcroPrep portfolio offers 24, 96, and 384-well high performance filter plates that result in fast sample flow and targeted size separation for efficient filtration, accurate separation, and reliable sample recovery all while minimizing crosstalk and extractable/leachables that can interfere with downstream analysis.  A comprehensive selection of membranes, sample well volumes, and tip configurations allows researchers to select the best filter plate that fits their specific application needs.  As your workflow evolves, Pall AcroPrep filter plates can scale with you in both sample volume and/or sample size without wasting time from membrane re-validation or product re-selection. 

Order Products

28 Products In Family
$ 75.60 - $ 475.20

AcroPrep™ Advance 96-Well filter plates for aqueous filtration with varied membrane and pore size selection allow for fast processing with efficient removal of particulates.

17 Products In Family
$ 22.90 - $ 1,445.04

AcroPrep™ 384-well Filter Plates are ideal for use in high volume, high throughput sample prep applications. Plates are constructed from chemically-resistant, biologically-inert polypropylene with a clear polystyrene lid.

13 Products In Family
$ 48.38 - $ 1,445.04

Optimized for a variety of applications requiring larger per well volume processing. Plates are constructed of chemicallyresistant, biologically-inert polypropylene.

12 Products In Family
$ 48.38 - $ 1,445.04

Superior bead recovery and low levels of false positives ensure assay reproducibility. Smooth well wall provides efficient bead recovery, ensuring reproducible results lot after lot.

8 Products In Family
$ 22.90 - $ 1,445.04

AcroPrep™ Advance Filter Plates for Lysate Clearance are manufactured with biologically inert materials that allow clarification of most types of lysates without loss of target molecules.

9 Products In Family
$ 22.90 - $ 1,445.04

The AcroPrep™ Advance filter plate portfolio includes a variety of membrane types and pore sizes to provide the best possible performance for a wide range of sample preparation and high throughput screening applications.

14 Products In Family
$ 22.90 - $ 1,445.04

Chemically resistant materials provide a stable platform to process samples in organic solvents. Inert materials of construction ensure complete recovery of samples and low non-specific binding.

18 Products In Family
$ 22.90 - $ 1,445.04

AcroPrep™ Advance 96-Well Filter Plates for Ultrafiltration provide rapid, efficient separation of biomolecules. Omega™ membrane provides high recovery and typically results in > 90% recovery of target biomolecules.

13 Products In Family
$ 22.90 - $ 1,445.04

Maximum yields of high quality DNA. Optimized for maximum binding yield of DNA from a variety of sample types. New well geometry results in reduced hold-up volume and higher recovery of DNA.

8 Products In Family
$ 22.90 - $ 1,445.04

The AcroPrep™ advance 96-well long tip filter plate for Nucleic Acid Binding (NAB plate) incorporates a silica-based quartz glass fiber media to allow for efficient binding of DNA and RNA, while providing smooth flow and rapid processing of samples.

6 Products In Family
$ 22.90 - $ 1,445.04

Description

The AcroPrepTM line of multi-well filter plates provide a superior platform for a multitude of laboratory applications. 

 

AcroPrep filter plates are designed to support the stringent requirements for high throughput applications and comply with the standards set forth by the Society of Biomolecular Screening (ANSI/SBS x-2004) for multi-well plates. Pall filter plates feature a rigid construction, which facilitates ease of use in automated systems. The rigidity of the plate prevents it from flexing and jamming in robotic processing units.

 

Plates are constructed from chemically resistant and biologically inert polypropylene, which means that plates are themselves low in binding to nucleic acids and proteins. The nature of the polypropylene housing also provides durability when using harsh organic solvents and will not contribute unwanted extractables or leachables. Additionally, the materials of construction have been tested to ensure that they do not contribute to ion suppression/enhancement. 

 

The patented design and unique sealing mechanism used in AcroPrep filter plates individually seals each well to prevent crosstalk (cross contamination from one well to another). Specially engineered fluid directors and outlet tips on the bottom of AcroPrep filter plates are designed to further reduce the potential for crosstalk.

 

The proprietary sealing technology provides flexibility in integrally sealing a variety of membranes and media in filter plates. This flexibility has allowed Pall to develop a wide array of plates that can meet developing customer needs.

  • Multi-well filter plates allow for high throughput and rapid sample processing
  • Filter plates can be utilized across a number of life science and analytical applications and workflows
  • Various filter choices – Specialized membranes and media accommodates a range of applications to guarantee success
  • Optimized outlet tips – Minimizes sample leakage during incubation steps and reduces the presence of hanging drops following filtration
  • Smooth well design – Provides consistency in filtration times, as well as efficient sample and bead recovery
  • Optimized well geometry – Results in fast, uniform filtration rates across filter plates, thereby improving well-to-well, plate-to-plate, and lot-to-lot consistency
  • Automation compatible – Manufactured in accordance with SBS guidelines, allowing plates to be run in manual, semi-automated, and automated processes
 

Pall supplies filter plates in 24, 96 and 384-well configurations with the following well volumes:

 

  Well Volume (max) Recommended Working Volume
AcroPrepTM 24-well Filter Plates 7 mL

7 mL for vacuum

6 mL for centrifugation

AcroPrepTM Advance 96-well Filter Plates 350 μL ≤ 300 μL
AcroPrepTM Advance 96-well Filter Plates, 1 mL 1 mL ≤ 900 μL
AcroPrepTM Advance 96-well Filter Plates, 2 mL 2 mL ≤ 1.9 mL
AcroPrepTM 384-well Filter Plates 100 µL 80 µL

 

Pall also offers a multi-well plate vacuum manifold that has been designed and optimized for vacuum filtration, and is a perfect fit for SBS-conforming filter plates. 

 

The manifold is constructed from durable anodized aluminum and comes complete with the necessary O-ring and gasket. The control block includes the vacuum pressure gauge, vacuum metering valve, vacuum release valve and the 1/4 inch hose barb for vacuum line attachment. Included with the vacuum manifold unit is a spacer block designed to accommodate standard 350 µL receiver plates. A spacer block that has been optimized to work with our 1 mL plate is available separately. 

Applications

Field Applications Membrane
Diagnostics Multiplex Assays Supor® (polyethersulfone) membrane
Diagnostics Flow Cytometry Sample Prep PP/PE non-woven (polypropylene/polyethylene) media
Nucleic Acids Plasmid DNA purification Silica-based quartz glass fiber
Nucleic Acids Genomic Purification Silica-based quartz glass fiber
Nucleic Acids Total RNA Purification Silica-based quartz glass fiber
Nucleic Acids PCR Clean-up OmegaTM (modified polyethersulfone) membrane
Nucleic Acids Labeling Clean-up Omega (modified polyethersulfone) membrane
Proteins Lysate Clarification Glass Fiber/Supor (polyethersulfone) membrane
Proteins Recombinant protein isolation Seitz® Depth Media/Supor EKV (hydrophilic polyethersulfone membrane)
Proteins Cell Clarification Seitz Depth Media/Supor EKV (hydrophilic polyethersulfone membrane)
Proteins Chromatography Screening Supor (polyethersulfone) membrane
Proteins Size Exclusion Omega (modified polyethersulfone) membrane
Proteins Concentration, Buffer Exchange, Desalting Omega (modified polyethersulfone) membrane
Proteins Protein Precipitation PTFE, wwPTFE (water-wettable polytetrafluoroethylene)
Proteins Sample Fractionation Mustang® Q, Mustang S
Proteins Free vs. Bound Assays Omega (modified polyethersulfone) membrane
Proteins Solid Phase ELISA BioTrace™ NT (nitrocellulose)
General Filtration Aqueous Filtration Supor (polyethersulfone) membrane, wwPTFE (water-wettable polytetrafluoroethylene)
General Filtration Sterile Filtration Supor EKV (Hydrophilic polyethersulfone membrane)
General Filtration Particulate Removal Glass Fiber
General Filtration Cell Separation PP/PE non-woven (polypropylene/polyethylene) media
General Filtration Solvent Filtration PTFE, wwPTFE (water-wettable polytetrafluoroethylene)

Literature Library

  • Datasheet: AcroPrep 24-well Filter Plates for Cell Clarification and Sterile Filtration

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  • Data Sheet: AcroPrep 24-well Filter Plates With Supor Membrane

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  • Datasheet: AcroPrep 24-well Filter Plates With Omega Membrane

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  • Poster: Use of 24-Well Filter Plates for Medium Throughput High Volume Sample Preparation Applications

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