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LV Centramate™ Lab Tangential Flow Filtration System product photo Primary L

LV Centramate™ Lab Tangential Flow Filtration System

Designed for Maximum Product Recovery for
Lab-Scale or Scale-Up Process Volumes up to 4 L

  • Scale-up/scale-down device for development of tangential flow filtration (TFF) processes, biopharmaceutical small batch production, scale-down investigations, and production of materials for safety and efficacy studies (Phase I clinicals).
  • Identical path lengths provide linear scale-up to Pall Centramate and Centrasette™ cassette holders. The LV Centramate holder may be attached to other laboratory TFF systems to improve their scalability characteristics.
  • Low hold-up volume allows high concentration factors to be achieved from small starting volumes. A complete TFF system scalable to full production plant can be optimized using the volumes typically generated in the development or discovery lab.
  • Easy connections through luer lock fitted ports with polished 316L stainless steel to ensure the same compatibility characteristics as production-scale Centrasette holders.
  • All product-wetted parts comply with pharmaceutical standards.

“Pall Laboratory products are designed for laboratory applications only. This product is not approved for use in medical, clinical, surgical or other patient applications. If you require further assistance in product selection for your chosen application, please contact Labcustomersupport@pall.com or call 1-800-521-1520."


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Cassettes

300K, 0.02 m² (0.2 ft²), screen (1/pkg)
List Price
$ 421.00
100K, 0.02 m² (0.2 ft²), screen (1/pkg)
List Price
$ 421.00
10K, 0.02 m² (0.2 ft²), screen (1/pkg)
List Price
$ 421.00
1K, 0.02 m² (0.2 ft²), screen (1/pkg)
List Price
$ 421.00
30K, 0.02 m² (0.2 ft²), screen (1/pkg)
List Price
$ 421.00
5K, 0.02 m² (0.2 ft²), screen (1/pkg)
List Price
$ 421.00

LV Centramate™ Cassette Holder

LV Centramate cassette holder (1/pkg)
List Price
$ 3,389.00

Omega™ Membrane LV Centramate™ Cassettes

List Price
$ 492.00
50K, 0.02 m² (0.2 ft²), screen (1/pkg)
List Price
$ 421.00
5K, 0.02 m² (0.2 ft²), suspended screen (1/pkg)
List Price
$ 411.00
70K, 0.02 m² (0.2 ft²), screen (1/pkg)
List Price
$ 421.00

Supor® Membrane LV Centramate™ Cassettes

List Price
$ 411.00
Description

Designed for Maximum Product Recovery for
Lab-Scale or Scale-Up Process Volumes up to 4 L

  • Scale-up/scale-down device for development of tangential flow filtration (TFF) processes, biopharmaceutical small batch production, scale-down investigations, and production of materials for safety and efficacy studies (Phase I clinicals).
  • Identical path lengths provide linear scale-up to Pall Centramate and Centrasette™ cassette holders. The LV Centramate holder may be attached to other laboratory TFF systems to improve their scalability characteristics.
  • Low hold-up volume allows high concentration factors to be achieved from small starting volumes. A complete TFF system scalable to full production plant can be optimized using the volumes typically generated in the development or discovery lab.
  • Easy connections through luer lock fitted ports with polished 316L stainless steel to ensure the same compatibility characteristics as production-scale Centrasette holders.
  • All product-wetted parts comply with pharmaceutical standards.

“Pall Laboratory products are designed for laboratory applications only. This product is not approved for use in medical, clinical, surgical or other patient applications. If you require further assistance in product selection for your chosen application, please contact Labcustomersupport@pall.com or call 1-800-521-1520."
Applications
  • Concentration of biomolecules
  • Recovery and purification of biomolecules from cell culture supernatants and lysates
  • Diafiltration, desalting, and buffer exchange of biomolecules
  • Fractionation of mixed molecule solutions
Specifications

Materials of Construction

  • Membrane Cassette Filter Media: Supor® [hydrophilic polyethersulfone (PES)], and Omega™ (low protein-binding, modified PES) membranes
  • Cassette Hardware
    • Cassette Holder Top and Bottom Plates: Type 316L stainless steel
    • Tie Rods and Washers: Type 304 stainless steel
    • Nuts: Bronze

Dimensions

  • Length: 22.8 cm (9 in.) Width: 8.3 cm (3.3 in.)

Typical Starting Volume

  • 0.02 m2 (0.2 ft2) cassette: 60 - 4,000 mL

Typical Hold-Up Volume

  • < 1 mL

Maximum Operating Temperature

  • 121 °C (250 °F)

Maximum Operating Pressure

  • 5 bar (500 kPa, 75 psi)

Typical Cross Flow Rate Per 0.02 m2 (0.2 ft2) Cassette (L/min)

  • Suspended Screen 0.2 - 0.4
  • Screen 0.12 - 0.16

Screen Selection Guideline

  • Suspended screen for light-tomoderate particle load solutions
  • Screen for optimized processing of particle-free protein solutions to high concentrations
Type
TFF System
Use
Ultrafiltration, Microfiltration
Application
Scalable TFF Systems
Segment
Tangential Flow Filtration