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AcroPak™ 500, 1000, & 1500 Capsules with Supor® Membrane product photo Primary L

AcroPak™ 500, 1000, & 1500 Capsules with Supor® Membrane

Fast, Final Filtration and High Throughputs
for Liquid Volumes Up To 150 L

  • Provides higher throughputs and faster flow rates than similarly-sized competitive devices
  • Ideal for solutions requiring low protein binding
  • Saves money by increasing throughput with available built-in prefilter
  • 100% integrity testing assures sterile filtrate
  • 0.1 μm Supor membrane version reduces mycoplasma levels in cell culture media
  • Fusion-welded components eliminate the potential for release of extractables from sealing adhesives
  • Sterilization by gamma irradiation eliminates potential contamination by EtO residuals

“Pall Laboratory products are designed for laboratory applications only. This product is not approved for use in medical, clinical, surgical or other patient applications. If you require further assistance in product selection for your chosen application, please email us a question or call 1-800-521-1520."

Video: Using an AcroPak Filter With a Peristaltic Pump



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AcroPak 1000 Capsules with Supor Membrane

AcroPak 1500 Capsules with Supor Membrane

AcroPak 500 Capsules with Supor Membrane

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Description

Fast, Final Filtration and High Throughputs
for Liquid Volumes Up To 150 L

  • Provides higher throughputs and faster flow rates than similarly-sized competitive devices
  • Ideal for solutions requiring low protein binding
  • Saves money by increasing throughput with available built-in prefilter
  • 100% integrity testing assures sterile filtrate
  • 0.1 μm Supor membrane version reduces mycoplasma levels in cell culture media
  • Fusion-welded components eliminate the potential for release of extractables from sealing adhesives
  • Sterilization by gamma irradiation eliminates potential contamination by EtO residuals

“Pall Laboratory products are designed for laboratory applications only. This product is not approved for use in medical, clinical, surgical or other patient applications. If you require further assistance in product selection for your chosen application, please email us a question or call 1-800-521-1520."

Video: Using an AcroPak Filter With a Peristaltic Pump

Specifications

Materials of Construction

  • Filter Media: Supor [hydrophilic polyethersulfone (PES)] membrane
  • Housing, Vent Plug, and Filter Support: Polypropylene
  • Sealing Technology: Thermal bonding
  • Filling Bell: Polycarbonate

Pore Size

  • 0.1/0.1, 0.2/0.2, 0.8/0.2, and 0.8/0.45 μm

Effective Filtration Area

  • 500 Series: 500 cm2
  • 1000 Series: 1000 cm2
  • 1500 Series: 1500 cm2

Dimensions

  • Housing Diameter: 6.9 cm (2.7 in.)
  • Overall Length (Without Filling Bell):
       500 Series: 14.5 cm (5.7 in.)
       1000 Series: 19.3 cm (7.6 in.)
       1500 Series: 22.9 cm (9.0 in.)

Inlet/Outlet Connections

  • 500 and 1000 Series: 6.4 - 12.7 mm (1/4 - 1/2 in.) stepped hose barb with filling bell on outlet
  • 1500 Series: 12.7 mm (1/2 in.) straight hose barb, no filling bell on outlet

Typical Hold-Up Volume (with 10 psi air purge)

  • 500 Series: 30 mL
  • 1000 Series: 45 mL

Maximum Operating Temperature

  • 60 °C (140 °F) at 2.1 bar (210 kPa, 30 psi)

Maximum Operating Pressure

  • Continuous: 4.1 bar (410 kPa, 60 psi) at ambient temperature

Recommended Integrity Test Minimum Bubble Point – Water

  • 0.2 μm: 3.5 bar (350 kPa, 51 psi)
  • 0.45 μm: 1.7 bar (170 kPa, 24 psi)
  • 60% IPA/40% H2O (v:v)
  • 0.1 μm: 2.4 bar (240 kPa, 35 psi)

Typical Water Flow Rate

  • Lpm at 0.1 bar (10 kPa) [Lpm/psi]:
     
    Pore Size 500 Series 1000 Series 1500 Series
    0.1/0.1 µm 0.2 (0.2) 0.4 (0.3) -
    0.2/0.2 µm 0.6 (0.4) 1.1 (0.8) 1.6 (1.1)
    0.8/0.2 µm 1.1 (0.8) 1.6 (1.1) 2.2 (1.5)
    0.8/0.45 µm 1.3 (0.9) 2.5 (1.7) -
     

Bacterial Retention

  • 0.1/0.1 μm Capsules: Lot samples retain a minimum of 107 cfu/cm2 of A. laidlawii challenge per modified ASTM F838, current revision
  • 0.2 μm Capsules: Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision

Endotoxin Level

  • < 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test

Biological Safety

  • Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>

Sterilization

  • Sterilized by gamma irradiation
  • If desired, autoclave once only prior to use at 121 - 123 °C (250 - 253 °F) for a maximum of 20 min.

Applications

  • Large-volume media preparation
  • Pilot-scale manufacturing
  • Liquids requiring prefiltration, such as serum-containing media
  • Sterile filtration of buffers
  • Point-of-use filtration for laboratory water
  • Reduce mycoplasma with the 0.1 µm pore size

 

 

Performance

Total Throughput Recorded for Devices with an EFA of Up to 1000 cm2


AcroPak Capsules With Supor Membrane Total Throughput

Throughput Determined using 3% TSB

Built-in Prefilter Enhances Total Throughput


AcroPak Capsules With Supor Membrane Enhanced Total Throughput

Membrane Type: 47 mm Disc
Throughput Determined using 2.5 % TSB

Type

Filter Capsules

Product Summary

Fast, final filtration and high throughputs for liquid volumes up to 150L. Ideal for solutions requiring low protein binding. Provides higher throughputs and faster flow rates than similarly-sized competitive devices.

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