Nylon Syringe Filters

Nylon syringe filters can be used for both aqueous and solvent-based sample filtration applications. They have excellent chemical compatibility with esters, bases and alcohols. Nylon syringe filters have been widely used to protect HPLC systems and columns from particulate contamination.

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ACRODISC PSF with 0.2µm Nylon 50/PK

Product ID: AP-4436TC
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.2 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Nylon
Hold-Up Volume
<125 µL
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ACRODISC PSF with 0.45µm Nylon 50/PK

Product ID: AP-4438TC
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Nylon
Hold-Up Volume
<125 µL
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Acrodisc® Syringe Filters with Nylon Membrane - 0.2 µm (50/pkg 200/cs)

Product ID: AP-4436
Unit of Measure
1/CV
Min Order Qty
1
Pore Size
0.2 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Nylon
Hold-Up Volume
<125 µL
See All Attributes

Acrodisc® Syringe Filters with Nylon Membrane - 0.45 µm (50/pkg 200/cs)

Product ID: AP-4438
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Nylon
Hold-Up Volume
<125 µL
See All Attributes

Acrodisc® Syringe Filters with Nylon Membrane - 0.45 µm (1000/pkg)

Product ID: AP-4502
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Nylon
Hold-Up Volume
<125 µL
Housing Material
polypropylene
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Acrodisc® Syringe Filters with Nylon Membrane - 0.45 µm, AutoPack tubes (25/pkg 200/cs)

Product ID: AP-4517
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Nylon
Hold-Up Volume
<125 µL
Housing Material
polypropylene
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Acrodisc® Syringe Filters with Nylon Membrane - GxF/0.45 µm, AutoPack tubes (25/pkg 200/cs)

Product ID: AP-4548
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Glass Fiber / Nylon
Hold-Up Volume
<425µL
Housing Material
polypropylene
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Acrodisc® Syringe Filters with Nylon Membrane - GxF/0.45 µm (50/pkg 200/cs)

Product ID: AP-4549
Unit of Measure
1/CV
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Glass Fiber / Nylon
Hold-Up Volume
<425 µL
See All Attributes

ACRODISC PSF w/ GFX/ 0.45µm Nylon 50/Pk

Product ID: AP-4549TC
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Glass Fiber / Nylon
Hold-Up Volume
<425µL
See All Attributes

Acrodisc® Syringe Filters with Nylon Membrane - 0.2 µm (1000/pkg)

Product ID: AP-4522
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.2 µm µm nominal
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Nylon
Hold-Up Volume
<125 µL
Housing Material
polypropylene
See All Attributes

Acrodisc® Syringe Filters with Nylon Membrane - GxF/0.45 µm (1000/pkg)

Product ID: AP-4528
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Glass Fiber / Nylon
Hold-Up Volume
<425µL
Housing Material
polypropylene
See All Attributes

ACRODISC PSF with GXF/0.2µm Nylon 50/PK

Product ID: AP-4787TC
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.2 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
3.9 cm²
Filter Media
Glass Fiber / Nylon
Hold-Up Volume
<425µL
See All Attributes

Description

Syringe filters are used in analytical chemistry applications to remove particulate contamination prior to analysis. Filtering a sample prior to sample injection into a HPLC machine will help protect sensitive parts of the instrument from particulate build-up and reduce system downtime. Sample filtration using syringe filters containing 0.45 μm (HPLC) or 0.2 μm (UHPLC) pore size membranes will also extend the life of chromatography columns.

 

The use of nylon syringe filters in analytical chemistry sample preparation has long been established. While newer HPLC syringe filter technology such as Pall’s Acrodisc® syringe filters with wwPTFE membrane which give significant chemical compatibility advantages are now available, nylon syringe filters continue to remain specified in to some protocols.

 

Nylon syringe filters can be used for both aqueous and solvent-based sample filtration applications and show excellent chemical compatibility with esters, bases and alcohols. However it should be noted that nylon syringe filters are not recommended for sample fluids which are strongly acidic.

 

Pall supply nylon syringe filters in different formats. The devices are all constructed from chemically compatible polypropylene. They are ideal for use in analytical chemistry filtration applications, such as HPLC/UHPLC and dissolution testing.

The 13 mm syringe filters are designed for the filtration of volumes up to 10 mL. 13 mm filters are available with a standard male slip luer outlet or Pall’s proprietary minispike outlet. The minispike allows for easy handling with a HPLC vial, and also offers a reduced hold-up volume, ensuring maximum filtrate recovery. 

 

Typical hold-up volumes:

 

  • 13 mm, male slip luer outlet: < 30 μl 
  • 13 mm, minispike: < 14 μl

 

Pall supplies both traditional ring moulded 25 mm nylon syringe filters and Premium Syringe Filter (PSF) 25 mm nylon syringe filters. The PSF syringe filter has a much larger effective filtration area compared with the older traditional model, 3.9 cm2 compared to 2.8 cm2. This gives the PSF syringe filter a much improved throughput and flow rate.

 

Nylon PSF syringe filters are available with a multi-layered glass fiber prefilter (GxF) above the nylon membrane. Syringe filters with the GxF configuration prefilter provide two to four times the throughput of standard prefilter devices for particulate-laden samples. This makes the filter ideal for applications in which there could be a high particulate load in the sample, for example in dissolution testing.

The 25 mm PSF filters have been designed and certified to meet the exacting requirements of automation systems. They demonstrate critical criteria including smooth filter-to-filter release, consistent turret advancement, exceptional housing strength and a strict outside filter geometry to ensure proper alignment and consistent operation. Autopack tube packaging is available for compatible automated equipment.

 

Pall‘s HPLC certification ensures that analytical results will not be compromised by extractable filter materials. To verify low levels of UV-detectable extractables, samples of the HPLC Acrodisc syringe filter line are randomly taken and tested for compatibility with common HPLC solvents using standard HPLC conditions.

Document

Datasheet

  • Tech Guide: Acrodisc Syringe Filters for Analytical Sample Preparation

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Applications

  • Versatile filters for both aqueous and solvent-based sample filtration
  • HPLC/UHPLC sample preparation
  • Dissolution testing

Specifications

Product Specifications Values

Acrodisc Syringe Filters with Nylon Membrane

Materials of Construction

Filter Media: Nylon

Housing: Polypropylene

GxF Prefilter: Borosilicate glass

Pore Size

Nylon Membrane: 0.2 and 0.45 μm

GxF Prefilter: 40 - 1 μm

Effective Filtration Area

13 mm: 1.0 cm2

25 mm PSF: 3.9 cm2

Inlet/Outlet Connections

13, and 25 mm PSF: Female luer

lock inlet, male slip luer outlet

13 mm: Available with minispike outlet

Maximum Operating Pressure

13 mm: 6.9 bar (690 kPa, 100 psi)

25 mm PSF: 4.1 bar (410 kPa,

60 psi) at 21 - 24 ºC (70 - 75 ºF);

2.1 bar (210 kPa, 30 psi) at

55 ºC (131 ºF)