PES Syringe Filters

Pall provides three types of non-sterile Acrodisc® Syringe Filters featuring the Supor® hydrophilic polyethersulfone (PES) membrane.

  • Acrodisc® syringe filters with Supor® membrane, modified acrylic housing
  • Acrodisc syringe filters with Supor membrane, polypropylene housing
  • Ion Chromatography (IC) Acrodisc® syringe filters

Supor membrane offer superior flow rates and high throughput. The membrane is low protein binding, making it suitable for the filtration of biological solutions.

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Product Use

HPLC/UHPLC SAMPLE PREPARATION

Product Use

Pre-Filtration

Acrodisc® Syringe Filter with Supor® Membrane - 0.8 µm, 25 mm modified acrylic housing (1000/pkg)

Product ID: 4509
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.8 µm µm nominal
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
2.8 cm²
Filter Media
Polyethersulfone (PES)
Hold-Up Volume
<300 µL
Housing Material
Modified acrylic
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Description

Non-sterile syringe filters with a Supor membrane in modified acrylic housing can be used for the filtration of general aqueous solutions. They are available in a 32 mm diameter, offering a large effective filtration area of 5.8 cm2. A range of different pore sizes from 0.2 μm to 5 μm are available to suit different application requirements.

The PSF (Premium Syringe Filter) 25 mm Supor syringe filters with polypropylene housing are ideal for use in analytical chemistry filtration applications, such as HPLC/UHPLC, dissolution testing, or other techniques in which a polyethersulfone membrane has been specified.

The Acrodisc PSF features a multi-layered glass fiber prefilter (GxF) above the Supor membrane. Syringe filters with the GxF configuration prefilter provide two to four times the throughput of standard prefilter devices for particulate-laden samples. This makes the filter ideal for applications in which there could be a high particulate load in the sample, for example in dissolution testing.

The PSF 25 mm filters have been designed and certified to meet the exacting requirements of automation systems. They demonstrate critical criteria including smooth filter-to-filter release, consistent turret advancement, exceptional housing strength and a strict outside filter geometry to ensure proper alignment and consistent operation. AutopackTM tube packaging is available for compatible automated equipment.

The Ion Chromatography (IC) Acrodisc syringe filters feature an optimized Supor membrane that has undergone several extra washing steps ensuring the product has low conductivity detectable extractables.

Sample filtration protects the IC system from various particulate materials, reduces system downtime, extends analytical column life, protects the injection port, and improves the accuracy and reproducibility of final results. For standard HPLC and IC systems using columns packed with 3 µm or larger particles, the recommended filtration standard is 0.45 µm for syringe filters. For columns with smaller packing material, microbore columns, or microbial growth concerns, an 0.2 µm filter product is recommended.

It is very important that products used in analytical sample preparation do not leach extractable materials which may lead to inaccurate results. In the case of ion chromatography, extractables may refer to any ionic components leaching from the filter materials. Extractables can cause several problems for chromatographers, foremost being inaccurate quantitation. Extractables may coelute with analyte peaks, causing false quantitation or extraneous peaks.

Pall IC Acrodisc syringe filters have been specifically designed and manufactured for IC applications. They are tested using a highly sensitive IC protocol to monitor inorganic extractables and are certified for low levels of inorganic extractables, with actual background levels of filter extractables that are typically less than 20 ppb for chloride, 6 ppb for nitrate, 1 ppb for phosphate, and 10 ppb for sulfate.

Pall IC Acrodisc syringe filters are available in 13 mm and PSF 25 mm diameters to suit the volume requirements of different sample sizes. The PSF 25 mm filters have been designed and certified to meet the exacting requirements of automation systems. Autopack tube packaging is available for compatible automated equipment.

Document

Datasheet

  • Tech Guide: Acrodisc Syringe Filters for Analytical Sample Preparation

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Applications

Acrodisc syringe filters with Supor membrane, modified acrylic housing

 

  • General aqueous non-sterile filtration
  • Larger pore size filters are used for prefiltration and particulate removal

 

Acrodisc syringe filters with Supor® membrane, Polypropylene housing

 

  • HPLC/UHPLC sample preparation
  • Dissolution testing

 

Ion Chromatography (IC) Acrodisc® syringe filters

 

  • Specifically designed for IC applications
  • Excellent filter selection for dissolution samples
  • Low drug and protein binding for pharmaceutical filtration
  • Supor (IC) membrane discs are recommended for aqueous samples only

Specifications

Product Specifications Values

Acrodisc® Syringe Filters With Supor® Membrane, modified acrylic housing

Materials of Construction

Filter Media: Supor membrane

(hydrophilic polyethersulfone)

Housing:

32 mm: Modified acrylic

Pore Size

Supor Membrane: 0.2, 0.45, 1.2,

and 5 μm

Effective Filtration Area

32 mm: 5.8 cm2

Inlet/Outlet Connections

Female luer lock inlet, male slip

luer outlet

Maximum Operating Pressure

32 mm: 5.2 bar (520 kPa, 75 psi)

Typical Water Flow Rate

mL/min at 3.1 bar (310 kPa, 45 psi)

32 mm, 0.2 μm: 490

32 mm, 0.45 μm: 560

32 mm, 0.8/0.2 μm: 440

32 mm, 1.2 μm: 1700

32 mm, 5 μm: 1750

 

Product Specifications Values

Acrodisc® Syringe Filters With Supor® Membrane, Polypropylene housing

Materials of Construction

Filter Media: Supor membrane

(hydrophilic polyethersulfone)

GxF Prefilter: Borosilicate glass

Housing:

25 mm PSF: Polypropylene

Pore Size

Supor Membrane: 0.2, 0.45 μm

GxF Prefilter: 40 - 1 μm

 

Effective Filtration Area

25 mm PSF: 3.9 cm2

 

Typical Sample Volume

25 mm PSF: < 150 mL

Inlet/Outlet Connections

Female luer lock inlet, male slip

luer outlet

Maximum Operating Pressure

25 mm PSF GxF: 4.1 bar (410 kPa,

60 psi) at 21 - 24 ºC (70 - 75 ºF);

2.1 bar (210 kPa, 30 psi) at

100 ºC (212 ºF)

 

Product Specifications Values
Ion Chromatography (IC) Acrodisc® Syringe Filters

Materials of Construction

Filter Media: Supor [hydrophilic polyethersulfone (PES)] membrane

Housing: Polypropylene

Pore Size

0.2 and 0.45 μm

Effective Filtration Area

13 mm: 1.0 cm2

25 mm PSF: 3.9 cm2

Typical Sample Volume

13 mm: < 10 mL

25 mm PSF: < 150 mL

Inlet/Outlet Connections

Female luer lock inlet, male slip luer outlet

Maximum Operating Pressure

13 mm: 6.9 bar (690 kPa, 100 psi)

25 mm PSF: 4.1 bar (410 kPa, 60 psi) at 21 - 24 ºC (70 - 75 ºF); 2.1 bar (210 kPa, 30 psi) at 100 ºC (212 ºF)

Typical Water Flow Rate

mL/min at 1.0 bar (100 kPa, 15 psi)

13 mm, 0.2 μm: 15

13 mm, 0.45 μm: 20

mL/min at 2.1 bar (210 kPa, 30 psi)

25 mm, 0.45 μm PSF: 420