PVDF Syringe Filters

Syringe filters containing hydrophilic PVDF (polyvinylidene fluoride) can be used for both aqueous and non-aggressive solvent-based sample filtration applications. PVDF syringe filters have been widely used to protect HPLC systems and columns from particulate contamination.

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Acrodisc® Syringe Filters with PVDF Membrane - 0.2 µm, 25mm (50/pkg, 200/cs)

Product ID: 4406
Unit of Measure
1/CV
Min Order Qty
1
Pore Size
0.2 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
2.8 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<100 µL
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ACRODISC 25mm w/ 0.45um PVDF 50pk

Product ID: 4408TC
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
2.8 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<100 µL
See All Attributes

ACRODISC 25mm w/ 0.2um PVDF 50pk

Product ID: 4406TC
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.2 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
2.8 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<100 µL
See All Attributes

Acrodisc® Syringe Filters with PVDF Membrane - 0.45 µm, 25mm (50/pkg 200/cs)

Product ID: 4408
Unit of Measure
1/CV
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Filter Size
25 mm
Diameter (Metric)
25 mm
Effective Filtration Area (Metric)
2.8 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<100 µL
See All Attributes

ACRODISC 13mm Mini w/ 0.2µm PVDF 100pk

Product ID: 4450TC
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.2 µm µm nominal
Filter Size
13 mm
Diameter (Metric)
13 mm
Effective Filtration Area (Metric)
1 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<14 µL
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Acrodisc® Syringe Filters with PVDF Membrane - 0.2 µm, 13mm, minispike outlet (100/pkg 300/cs)

Product ID: 4450
Unit of Measure
1/CV
Min Order Qty
1
Pore Size
0.2 µm µm nominal
Filter Size
13 mm
Diameter (Metric)
13 mm
Effective Filtration Area (Metric)
1 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<14 µL
See All Attributes

Acrodisc® Syringe Filters with PVDF Membrane - 0.45 µm, 13mm, minispike outlet (100/pkg 300/cs)

Product ID: 4452
Unit of Measure
1/CV
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Filter Size
13 mm
Diameter (Metric)
13 mm
Effective Filtration Area (Metric)
1 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<14 µL
See All Attributes

ACRODISC 13mm Mini w/ 0.45µm PVDF 100pk

Product ID: 4452TC
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Filter Size
13 mm
Diameter (Metric)
13 mm
Effective Filtration Area (Metric)
1 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<14 µL
See All Attributes

ACRODISC 13mm with 0.2µm PVDF 100/PK

Product ID: 4455TC
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.2 µm µm nominal
Filter Size
13 mm
Diameter (Metric)
13 mm
Effective Filtration Area (Metric)
1 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<30 µL
See All Attributes

ACRODISC 13mm with 0.45µm PVDF 100/PK

Product ID: 4457TC
Unit of Measure
1/PAC
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Filter Size
13 mm
Diameter (Metric)
13 mm
Effective Filtration Area (Metric)
1 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<30 µL
See All Attributes

Acrodisc® Syringe Filters with PVDF Membrane - 0.2 µm, 13mm, male slip luer outlet (100/pkg 300/cs)

Product ID: 4455
Unit of Measure
1/EA
Min Order Qty
1
Pore Size
0.2 µm µm nominal
Filter Size
13 mm
Diameter (Metric)
13 mm
Effective Filtration Area (Metric)
1 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<30 µL
See All Attributes

Acrodisc® Syringe Filters with PVDF Membrane - 0.45 µm, 13mm, male slip luer outlet (100/pkg 300/cs)

Product ID: 4457
Unit of Measure
1/CV
Min Order Qty
1
Pore Size
0.45 µm µm nominal
Filter Size
13 mm
Diameter (Metric)
13 mm
Effective Filtration Area (Metric)
1 cm²
Filter Media
Hydrophilic polyvinylidene fluoride (PVDF)
Hold-Up Volume
<30 µL
See All Attributes

Description

Syringe filters are used in analytical chemistry applications to remove particulate contamination prior to analysis. Filtering a sample prior to injection into a HPLC machine will help protect sensitive parts of the instrument from particulate build up and reduce system downtime.

 

Sample filtration using syringe filters containing 0.45 μm (HPLC) or 0.2 μm (UHPLC) pore size membranes will also extend the life of chromatography columns. High performance columns are composed of small particles of narrow size distribution. Optimal peak profiles depend on column operating characteristics and should be instrument independent. Filtration can prevent particulate contamination of a column, and avoid physical changes occurring such as blocked frits or channel voids in the column packing.

 

The use of PVDF syringe filters in analytical chemistry sample preparation has long been established. While newer analytical chemistry syringe filter technology such as Pall’s Acrodisc® syringe filters with wwPTFE membrane which give significant chemical compatibility advantages are now available, PVDF syringe filters continue to remain specified in some older protocols.

Pall supply PVDF syringe filters in different formats. The devices are all constructed from chemically compatible polypropylene. They are ideal for use in analytical chemistry filtration applications, such as HPLC/UHPLC and dissolution testing.

 

PVDF syringe filters offer excellent chemical compatibility, including aggressive acids and alcohols. However they are not recommended for the filtration of acetone, DMF, DMSO, or strong bases.

Typical hold-up volumes:

13 mm, male slip luer outlet: < 30 μm

13 mm, minispike: < 14 μm

 

Pall supply both traditional ring moulded 25 mm PVDF syringe filters and PSF (Premium Syringe Filter) 25 mm PVDF syringe filters. The PSF syringe filter has a much larger effective filtration area compared with the older traditional model, 3.9 cm2 compared to 2.8 cm2. This gives the PSF syringe filter a much improved throughput and flow rate.

 

PVDF PSF syringe filters are available with a multi-layered glass fiber prefilter (GxF) above the PVDF membrane. Syringe filters with the GxF configuration prefilter provide two to four times the throughput of standard prefilter devices for particulate-laden samples. This makes the filter ideal for applications in which there could be a high particulate load in the sample, for example in dissolution testing.

The 25 mm PSF filters have been designed and certified to meet the exacting requirements of automation systems. They demonstrate critical criteria including smooth filter-to-filter release, consistent turret advancement, exceptional housing strength and a strict outside filter geometry to ensure proper alignment and consistent operation. AutopackTM tube packaging is available for compatible automated equipment.

 

Pall Life Sciences HPLC certification ensures that analytical results will not be compromised by extractable filter materials. To verify low levels of UV-detectable extractables, samples of the HPLC Acrodisc syringe filter line are randomly taken and tested for compatibility with common HPLC solvents using standard HPLC conditions.

Document

Datasheet

  • Tech Guide: Acrodisc Syringe Filters for Analytical Sample Preparation

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Applications

  • Versatile filters for both aqueous and solvent-based sample filtration
  • HPLC/UHPLC sample preparation
  • Dissolution testing

Specifications

Product Specifications Values

PVDF Syringe Filters

Materials of Construction

Filter Media: Hydrophilic polyvinylidene fluoride (PVDF)

Housing: Polypropylene

GxF Prefilter: Borosilicate glass

Pore Size

PVDF Membrane: 0.2 and 0.45 μm

GxF Prefilter: 40 - 1 μm

Effective Filtration Area

13 mm: 1.0 cm2

25 mm PSF: 3.9 cm2

Inlet/Outlet Connections

13 and 25 mm PSF: Female luer lock

inlet, male slip luer outlet

13 mm: Available with minispike outlet

Maximum Operating Pressure

13 mm: 3.5 bar (350 kPa, 50 psi)

25 mm PSF: 4.1 bar (410 kPa, 60 psi)

at 21 - 24 ºC (70 - 75 ºF);

2.1 bar (210 kPa, 30 psi) at

82 ºC (180 ºF)

Typical Water Flow Rate

mL/min at 3.1 bar (310 kPa, 45 psi)

13 mm, 0.2 μm: 5

13 mm, 0.45 μm: 15

mL/min at 2.1 bar (210 kPa, 30 psi)

25 mm, 0.45 μm PSF and GxF: 144