wwPTFE Syringe Filters (Acrodisc® Syringe Filters with Universal Membranes)

Choosing the correct syringe filter for HPLC/UHPLC sample filtration can sometimes be challenging. There are many different membrane choices and devices in the marketplace. Pall have simplified syringe filter selection by offing Acrodisc® syringe filters with universal membranes that are suitable for all HPLC/UHPLC analytical sample preparation filtration requirements.

These syringe filters feature a universally solvent compatible membrane in a chemically compatible housing, users need only select pore size and device size.

wwPTFE Acrodisc Syringe Filters, family

Product images are a representation of product family for illustration purposes only. Actual products may vary.

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Red1000 Glass Fiber 12 micron (Beta 1000) Nitrile 36in 91.44cm

Product ID: HC2296FKS36H
Unit of Measure
1/EA
Min Order Qty
6
Anti-Static
No
Beta Rating
BETA 1000
Element Series
HC2296
Family
Red1000
Filter Media
Glass Fiber
Filter Removal Rating (μm)
12 µm
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Ultipor III Glass Fiber 5 micron (Beta 1000) Nitrile 8in 20.32cm length

Product ID: HC9601FDP8H#28
Unit of Measure
1/EA
Min Order Qty
1
Anti-Static
No
Beta Rating
BETA 1000
Element Series
HC9601
Family
Ultipor III
Filter Media
Glass Fiber
Filter Removal Rating (μm)
5 µm
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RT250A10S product photo

RT250A10S

Product ID: RT250A10S
Unit of Measure
1/EA
Min Order Qty
1
Packaging
Bulk
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Claris® Filter Cartridge, 5 µm, 40 in, Single Open Ended with Fin End and External 222 O-rings

Product ID: CLR540M8WS480
Unit of Measure
12/EA
Min Order Qty
12
Removal Rating
5 µm
Membrane Material
Polypropylene
Cartridge Length (Imperial)
40 in
Cartridge Length (Metric)
762 mm
Cartridge Length (Metric)
76.2 cm
Gasket / O-Ring Material
Silicone Elastomer
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Claris® Filter Cartridges, Removal Rating 5 μm, Polypropylene, Length 50 inches, silicone

Product ID: CLR550M3S815
Unit of Measure
308/EA
Min Order Qty
308
Removal Rating
5 µm
Membrane Material
Polypropylene
Cartridge Length (Imperial)
50 in
Cartridge Length (Metric)
1270 mm
Cartridge Length (Metric)
127 cm
Gasket / O-Ring Material
Silicone
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Claris® Filter Cartridges, Removal Rating 5 μm, Polypropylene, Length 50 inches product photo

Claris® Filter Cartridges, Removal Rating 5 μm, Polypropylene, Length 50 inches

Product ID: CLR550
Unit of Measure
20/EA
Min Order Qty
20
Micron
5 micron
Length
127 cm / 50 in

Claris® Filter Cartridges, Removal Rating 5 μm, Polypropylene, Length 9.875 inches

Product ID: CLR59875
Unit of Measure
36/EA
Min Order Qty
36
Removal Rating
5 µm
Membrane Material
Polypropylene
Cartridge Length (Imperial)
9.875 in
Cartridge Length (Metric)
251 mm
Cartridge Length (Metric)
25.1 cm
Gasket / O-Ring Material
NA
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Claris® Filter Cartridge, CLR540W480

Product ID: CLR540W480
Unit of Measure
24/EA
Min Order Qty
24
Removal Rating
5 µm
Membrane Material
Polypropylene
Cartridge Length (Imperial)
40 in
Cartridge Length (Metric)
1016 mm
Cartridge Length (Metric)
101.6 cm
Gasket O-Ring Code
Blank
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Claris® Filter Cartridges, Removal Rating 75 μm, Polypropylene, Length 19.5 inches product photo

Claris® Filter Cartridges, Removal Rating 75 μm, Polypropylene, Length 19.5 inches

Product ID: CLR75195
Unit of Measure
24/EA
Min Order Qty
24
Micron
75 micron
Length
49.5 cm / 19.5 in

Claris® Filter Cartridges, Removal Rating 5 μm, Polypropylene, Length 50 inches, DOE Santoprene gasket seal

Product ID: CLR550H21
Unit of Measure
10/EA
Min Order Qty
10
Removal Rating
5 µm
Membrane Material
Polypropylene
Cartridge Length (Imperial)
50 in
Cartridge Length (Metric)
1270 mm
Cartridge Length (Metric)
127 cm
Gasket / O-Ring Material
NA
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CLR 75-10-H21

Product ID: CLR7510H21
Unit of Measure
36/EA
Min Order Qty
72

Claris® Filter Cartridges, Removal Rating 75 μm, Polypropylene, Length 30 inches, EPDM

Product ID: CLR7530M3E
Unit of Measure
12/EA
Min Order Qty
24
Removal Rating
75 µm
Membrane Material
Polypropylene
Cartridge Length (Imperial)
30 in
Cartridge Length (Metric)
762 mm
Cartridge Length (Metric)
76.2 cm
Gasket / O-Ring Material
EPDM
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Description

Sample filtration is a simple and economical practice that serves to extend the life of consumable HPLC parts, decrease system wear and tear, and preserve the integrity of the HPLC system. Filtering a sample prior to sample injection into a HPLC will help protect sensitive parts of the instrument from particulate build up and reduce system downtime. Sample filtration using syringe filters containing 0.45 μm (HPLC) or 0.2 μm (UHPLC) pore size membranes will also extend the life of chromatography columns. 

 

High performance columns are composed of small particles of narrow size distribution. Optimal peak profiles depend on column operating characteristics and should be instrument independent. Columns, depending on sample type, sample preparation, and operator filtration practices, can handle a few to several thousand injections. Two significant problems with HPLC columns are chemical and physical changes. Chemical changes are prevented with guard columns. Physical changes involve blocked frits and channel voids created by particulate matter build up. 

 

Pall’s Acrodisc syringe filters with universal membranes have been designed to protect analytical instrumentation and improve the reliability of results. These syringe filters contain the universally solvent compatible wwPTFE (water wettable Polytetrafluoroethylene) membrane and are suitable for use in both aqueous and organic applications.

 

These syringe filters are constructed with solvent compatible polypropylene material. The polypropylene plastic provides the syringe filter with exceptional strength, it is the highest grade of plastic with minimal additives, and passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88> plastics testing.

 

Both the wwPTFE membrane and polypropylene housing are extremely low in levels of potential extractables that can lead to chromatographic interference. The devices are low in protein and API binding which make them ideal for drug studies, such as dissolution testing.

 

Pall provides HPLC certification with these products, ensuring that analytical results will not be compromised by extractable filter materials. Pall membranes are tested for compatibility with common HPLC solvents including water, methanol, and acetonitrile, using established HPLC procedures. In addition, to verify low levels of UV-detectable extractables, samples of the syringe filters are evaluated prior to release.

Pall’s Acrodisc syringe filters with universal membranes are available in 13 mm and 25 mm diameters to suit the volume requirements of different applications. The 13 mm devices feature Pall’s proprietary minispike outlet configuration, it offers a lower hold-up volume and easier filtration into autosampler vials compared to standard luer outlets.

The 25 mm device, Acrodisc One™ syringe filter with wwPTFE membrane, sets the standard for HPLC/UHPLC analytical filtration. It can extend the life of a HPLC column by up to 52 times over unfiltered samples.

Effects of filters on HPLC column life following injections of unfiltered and filtered 0.05% latex sphere suspensions. With unfiltered samples, the column failed due to plugging after 19 injections. Samples passed through competitor filters plugged the columns after 500 injections. No increase in backpressure was observed after 1000 injections of samples filtered with Pall Acrodisc One™ syringe filters.

 

Acrodisc One syringe filters are available with either 0.45 μm (HPLC) or 0.2 μm (UHPLC) pore size wwPTFE membranes. For solutions with high particulate load Pall supply a version of the Acrodisc One with a multi-layered glass fiber prefilter (GxF) above the wwPTFE membrane. Syringe filters with the GxF configuration prefilter provide two to four times the throughput of standard prefilter devices for particulate-laden samples.

Acrodisc One syringe filters have been designed and certified to meet the exacting requirements of automation systems. They demonstrate critical criteria including smooth filter-to-filter release, consistent turret advancement, exceptional housing strength and a strict outside filter geometry to ensure proper alignment and consistent operation. AutopackTM tube packaging is available for compatible automated equipment.

 

 

Pall’s Acrodisc Syringe Filters With Universal Membranes are suitable for all of your HPLC/UHPLC analytical filtration requirements.

 

  • Automation certified to ensure smooth operation and worry-free performance 24 hours a day in automated workstations
  • Avoid the expense and inconvenience of keeping a variety of filters on hand. Versatile filter for aqueous and aggressive organic solvent-based solutions
  • Low protein binding membrane gives high recovery of critical proteinaceous samples
  • Accurate analysis. HPLC certified for low levels of UV-absorbing extractables
  • Easy filtration of particulate-laden samples with glass fiber prefilter version
  • 13 mm Acrodisc syringe filter with minispike configuration offers low hold-up and easy filtration into autosampler vials
  • Protects columns and instrumentation from particulate build-up better than other filters

Documents

Datasheets

  • App Note: Acrodisc One Syringe Filter with wwPTFE Membrane Compared to Regenerated Cellulose Syringe Filters

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    By clicking the Submit or Download button below and proceeding I confirm that I have reviewed and agree with the Terms of Use and the Privacy Policy.

  • App Note: Acrodisc One Syringe Filter with wwPTFE Membrane Compared to Low Cost Hydrophilic PTFE Syringe Filters

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    Country
    • Afghanistan
    • Albania
    • Algeria
    • American Samoa
    • Andorra
    • Angola
    • Anguilla
    • Antarctica
    • Antigua and Barbuda
    • Argentina
    • Aruba
    • Australia
    • Austria
    • Bahamas
    • Bahrain
    • Bangladesh
    • Barbados
    • Belgium
    • Belize
    • Benin
    • Bermuda
    • Bhutan
    • Bolivia
    • Botswana
    • Brazil
    • British Indian Ocean Territory
    • Brunei Darussalam
    • Bulgaria
    • Burkina Faso
    • Burundi
    • Cambodia
    • Cameroon
    • Canada
    • Cape Verde
    • Cayman Islands
    • Chad
    • Chile
    • China
    • Christmas Island
    • Cocos (Keeling) Islands
    • Colombia
    • Comoros
    • Cook Islands
    • Costa Rica
    • Croatia
    • Cuba
    • Cyprus
    • Czech Republic
    • Denmark
    • Djibouti
    • Dominica
    • Dominican Republic
    • Ecuador
    • Egypt
    • El Salvador
    • Equatorial Guinea
    • Eritrea
    • Estonia
    • Ethiopia
    • Falkland Islands
    • Faroe Islands
    • Fiji
    • Finland
    • France
    • French Guiana
    • French Polynesia
    • French Southern Territories
    • Gabon
    • Gambia
    • Germany
    • Ghana
    • Gibraltar
    • Greece
    • Greenland
    • Grenada
    • Guadeloupe
    • Guam
    • Guatemala
    • Guinea
    • Guinea-Bissau
    • Guyana
    • Haiti
    • Honduras
    • Hong Kong
    • Hungary
    • Iceland
    • India
    • Indonesia
    • Iraq
    • Ireland
    • Israel
    • Italy
    • Jamaica
    • Japan
    • Jordan
    • Kenya
    • Kiribati
    • Kuwait
    • Laos
    • Latvia
    • Lebanon
    • Lesotho
    • Liberia
    • Libya
    • Liechtenstein
    • Lithuania
    • Luxembourg
    • Macao
    • Madagascar
    • Malawi
    • Malaysia
    • Maldives
    • Mali
    • Malta
    • Marshall Islands
    • Martinique
    • Mauritania
    • Mauritius
    • Mayotte
    • Mexico
    • Monaco
    • Mongolia
    • Montserrat
    • Morocco
    • Mozambique
    • Myanmar
    • Namibia
    • Nauru
    • Nepal
    • Netherlands
    • Netherlands Antilles
    • New Caledonia
    • New Zealand
    • Nicaragua
    • Niger
    • Nigeria
    • Niue
    • Norfolk Island
    • Northern Mariana Islands
    • Norway
    • Oman
    • Pakistan
    • Palau
    • Palestinian Territory
    • Panama
    • Papua New Guinea
    • Paraguay
    • Peru
    • Philippines
    • Poland
    • Portugal
    • Puerto Rico
    • Qatar
    • Romania
    • Rwanda
    • Samoa
    • Saudi Arabia
    • Senegal
    • Seychelles
    • Sierra Leone
    • Singapore
    • Slovakia
    • Slovenia
    • Solomon Islands
    • Somalia
    • South Africa
    • Spain
    • Sri Lanka
    • St Kitts and Nevis
    • St Lucia
    • Sudan
    • Suriname
    • Swaziland
    • Sweden
    • Switzerland
    • Taiwan
    • Thailand
    • Togo
    • Tonga
    • Trinidad and Tobago
    • Tunisia
    • Turkey
    • Tuvalu
    • Uganda
    • United Arab Emirates
    • United Kingdom
    • United States
    • Uruguay
    • Vanuatu
    • Venezuela
    • Vietnam
    • Virgin Islands
    • Western Sahara
    • Yemen
    • Zambia
    • Zimbabwe

    By clicking the Submit or Download button below and proceeding I confirm that I have reviewed and agree with the Terms of Use and the Privacy Policy.

  • Tech Guide: Acrodisc Syringe Filters for Analytical Sample Preparation

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Applications

  • Highly recommended for filtering HPLC samples
  • Available in 0.2 μm for UHPLC applications
  • 25 mm Acrodisc PSF syringe filter is available in robotic-compatible AutoPack™ packaging

Specifications

Product Specifications Values

Acrodisc® Syringe Filters with Universal Membranes

Materials of Construction

Filter Media: Water wettable polytetrafluoroethylene (wwPTFE), GH Polypro membrane (GHP, hydrophilic polypropylene)

Housing: Polypropylene

GxF Prefilter: Binder-free borosilicate glass

Pore Size

0.2 and 0.45 μm

Glass Fiber: 1 μm

GxF Prefilter: 40 - 1 μm

Effective Filtration Area

13 mm: 1.0 cm2

25 mm: 2.8 cm2

25 mm PSF: 3.9 cm2

Typical Sample Volume

13 mm: < 10 mL

25 mm PSF: < 150 mL

Inlet/Outlet Connections

13 mm: Female luer inlet, minispike outlet

25 mm PSF: Female luer inlet, male slip luer outlet

FAQs

1. Are Pall’s wwPTFE non-sterile syringe filters suitable for medical applications?

No, Pall’s wwPTFE non-sterile syringe filters are advisable to be used in laboratory and manufacturing industry applications only. They are not suitable for medical, clinical, surgical, or other patient applications.

 

2. How do I ensure the safety of wwPTFE non-sterile sterile syringe filters from accidental contamination through external sources?

Acrodisc syringe filters are packaged into separate tubes to protect them from external sources of extractables. While one tube is in use, others can be kept sealed.

 

3. How do wwPTFE membranes deliver reliable and accurate results?

The Acrodisc wwPTEF non-sterile syringe filter minimizes the risk of ion suppression and enhancement, and deliver reliable and accurate results.