Contamination Analysis product photo Primary L

Contamination Analysis

The presence of unexpected particulate or microbial contaminants in process fluids can lead to system failure, batch reprocessing, or even batch rejection. It is critical that these contaminants be quickly isolated and identified, so that possible sources can be traced and corrective actions applied to the process.

How Can Pall Help?

Pall has over fifty years experience in contamination analysis and control and offers a range of standard services for analysis of particulate and microbial contaminants.

In the simplest form, we can often provide the necessary advice and corrective actions by telephone or via e-mail. Alternatively, samples can be sent to a Pall facility for analysis or we can sample on site. These investigations will be fully documented and a technical report is supplied following conclusion of the test work and process review, to ensure that any change control is correctly managed and implemented.

Microbiological Contaminants

The isolation and identification of microbiological contaminants from process fluids
requires specialist laboratory facilities and expertise, all of which can be offered by Pall Life Sciences.

Typical microbiological studies include:
  • Total bacterial count
  • Bioburden analysis 
  • Identification and review of process isolates

Particulate Contaminants

Pall Life Sciences have available a wide range of microscopic and analytical equipment for the analysis of particulate and/or amorphous contaminants including:
  • Optical microscopy
  • Scanning electron microscopy
  • X-Ray emission spectroscopy
  • Computer-enhanced image analysis

Analysis of Process Bioburden

The full quantification and identification of natural process bioburden is of increasing regulatory interest. Some bacteria, when subjected to particular environmental conditions, are known to produce particularly diminutive forms capable of penetrating 0.2 µm sterilizing grade filter cartridges.

A typical analysis procedure is as follows:
  • Filter samples through 47 mm diameter analysis discs
  • Place discs on nutrient agar plates and incubate
  • Count colonies to quantify bioburden Strike out individual colony types
  • Examine colony morphology
  • Gram stain and examine microscopically
  • Perform biochemical tests to establish identity
  • Document and report results


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Description
The presence of unexpected particulate or microbial contaminants in process fluids can lead to system failure, batch reprocessing, or even batch rejection. It is critical that these contaminants be quickly isolated and identified, so that possible sources can be traced and corrective actions applied to the process.

How Can Pall Help?

Pall has over fifty years experience in contamination analysis and control and offers a range of standard services for analysis of particulate and microbial contaminants.

In the simplest form, we can often provide the necessary advice and corrective actions by telephone or via e-mail. Alternatively, samples can be sent to a Pall facility for analysis or we can sample on site. These investigations will be fully documented and a technical report is supplied following conclusion of the test work and process review, to ensure that any change control is correctly managed and implemented.

Microbiological Contaminants

The isolation and identification of microbiological contaminants from process fluids
requires specialist laboratory facilities and expertise, all of which can be offered by Pall Life Sciences.

Typical microbiological studies include:
  • Total bacterial count
  • Bioburden analysis 
  • Identification and review of process isolates

Particulate Contaminants

Pall Life Sciences have available a wide range of microscopic and analytical equipment for the analysis of particulate and/or amorphous contaminants including:
  • Optical microscopy
  • Scanning electron microscopy
  • X-Ray emission spectroscopy
  • Computer-enhanced image analysis

Analysis of Process Bioburden

The full quantification and identification of natural process bioburden is of increasing regulatory interest. Some bacteria, when subjected to particular environmental conditions, are known to produce particularly diminutive forms capable of penetrating 0.2 µm sterilizing grade filter cartridges.

A typical analysis procedure is as follows:
  • Filter samples through 47 mm diameter analysis discs
  • Place discs on nutrient agar plates and incubate
  • Count colonies to quantify bioburden Strike out individual colony types
  • Examine colony morphology
  • Gram stain and examine microscopically
  • Perform biochemical tests to establish identity
  • Document and report results
Performance

Typical Investigation Procedure for Particulate Contaminants in
a Water System

SEM Showing Contamination Retained by Filter Membrane

Type
Services
Use
Testing, Diagnostics
Ordering Information

Charges

Wherever possible, we provide a fixed price in advance for the project. Where this is not possible, we will give an estimate to assist you in budgeting and cost control. The final invoice gives details on items such as labor, and materials.

Part Number Structure

Pall's part number structure is for reference during the ordering process. A Pall representative will assign the specific service part number applicable to your service requirements.


Typical Part Number: PTS04AE (Contamination analysis with scanning electron microscopy and XES).

What’s the Next Step?

Please contact Pall. A representative will discuss your specific requirements with you and forward your enquiry to Pall contamination analysis specialists.

Application
General F&B, General F&B, Particulate Control, Final Membrane Filter for Microbial Reduction, Carbon Dioxide Filtration for Sparkling Wine, Integrity Testing, General F&B, General F&B, General F&B, General F&B, QC Microbial Detection - Pathogens, QC Microbial Detection - Pathogens, QC/Microbial Detection - Spoilage, QC/Microbial Detection - Spoilage, Microbial Protection for Water Bottlers, QC/Microbial Detection - Spoilage, QC/Microbial Detection - Spoilage, QC/Microbial Detection - Spoilage, QC Microbial Detection - Pathogens, QC/Microbial Detection - Spoilage, QC/Microbial Detection - Spoilage, QC Microbial Detection - Pathogens, Beverage Spoilage, Food Safety, Environmental Monitoring, Protection for European Mineral Water Bottlers, Cheese Brine, Water, Carbon Dioxide Filtration, Vent Filtration, Utilities Filtration, Laboratory Analysis, Bacteria Removal , Milk Fractionation , Whey Defatting , Incoming Water Primary Filtration, Lactic Curd Concentration, Whole Milk Concentration, CIP Recovery, Barrel Char Removal, Chill Haze Removal/Stabilization, Activated Carbon Treatment for Odor Removal, Activated Carbon Treatment for Color Removal, Activated Carbon Removal, Guard Filtration, Particle Removal, Coarse Filtration, Color Removal, Color Adjustment, Removal of Off Odors and Off Flavors, Neutralization of T Spirits, Fermentation Broth Clarification, Mud Removal , Fruit Juice Clarification , Gelatin or Collagen Clarification, Stick Water from Slautherhouse, Fish Processing, Plant Extract/Plant Protein Clarification, Tanker Off Loading, Incoming Water Treatment, Particulate Control for Flavor Additive, Carbon Dioxide Filtration, Vent Filtration, Utilities Filtration, Laboratory Analysis, Incoming Water: Primary Filtration, Water: Trap Filtration, RO Protection, Water Polishing Filtration, Trap Filtration, Concentrate Filtration, Flavor Additive Filtration, Citrus Oil Removal, Post Mixing Filtration, Storage Tank Protection (Venting), Trap Filter (Sugar Syrup), Clarification, Protein Stabilization, Lees Filtration (Recovery of wine and juice from lees), Polishing Filtration/Colloid Removal, Pre RO filtration, Prefiltration, Final filtration/Microbial Stabilization, Rinse/CIP Water Filtration, Yeast Screening & Identification, Filtration after Cold Stabilization, Color/Flavor Adjustment, Integrity Testing, Clarification, Polishing Filtration, Prefiltration, Pre Storage and Prefiltration, Final Filtration/Microbial Stabilization, Integrity Testing, Water Filtration, Tank Vent/Air Filtration, Yeast Screeing and Identification, Clarification, Lees Filtration/Alcohol Recovery from Yeast Bottoms, Polish Filtration, Prefiltration, Final Filtration/Microbial Stabilization, Mineral/Flavor Filtration, Rinse/CIP water filtration, Incoming Water, Service Media Filtration, Preclarification, Clarification, Final Filtration, PROFi, Microcontrol with PCR, Incoming Water, Service Media Filtration, Fine Filtration: Colloid Reduction, Clarification, Stabilization, Particle Filtration, Fine Filtration, Beer Sterile Filtration, Beer Recovery, Continuous Processing, Microcontrol with PCR, Yeast Screening & Identification, Carbon Dioxide Filtration
Segment
Beer (Corporate)
Beer (Craft/Micro Breweries)
Bottled Water
Cider
Dairy
Food Contact Compliance & Safety
Food and Ingredients
Juice
Pet Food
Quality Control
Soft Drinks
Spirits
Wine