Gas Filters

Sterilizing-grade gas filters protect biopharmaceutical products from contamination by microorganisms or particles during processes such as gas venting from tanks or bioreactors, compressed gas filtration and high-temperature or highly oxidizing applications. Non-sterilizing-grade filters reduce bioburden for non-critical applications or act as prefilters protecting a sterilizing-grade filter downstream.

 

Shop Gas Filters

 

Emflon II

Emflon® PFR

Emflon HTPFR

HDC II

Emflon PFA

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Sterilization Option(s)

Suitable for Autoclave

Product Use

Air, Gas, and Vent Filtration

Emflon® PFR membrane in Mini Kleenpak™ capsules, 0.2 µm sterilizing grade, 280 cm² EFA, ½ in. Triclover-compatible connections, box of 3 product photo

Emflon® PFR membrane in Mini Kleenpak™ capsules, 0.2 µm sterilizing grade, 280 cm² EFA, ½ in. Triclover-compatible connections, box of 3

Product ID: KA02PFRP8
Unit of Measure
1/EA
Min Order Qty
1
Sterilization Option(s)
Suitable for Autoclave
Removal Rating
0.2 µm
See All Attributes
Acro® 50 vent filters, 0.2 µm sterilizing grade, 19.6 cm² EFA, ½-¼ in. stepped hose barb connections, box of 72 product photo

Acro® 50 vent filters, 0.2 µm sterilizing grade, 19.6 cm² EFA, ½-¼ in. stepped hose barb connections, box of 72

Product ID: 6074270L
Unit of Measure
1/PAC
Min Order Qty
1
Removal Rating
0.2 µm
Membrane Material
PTFE
Effective Filtration Area (Metric)
19.6 cm²
See All Attributes

Description

Pall® Gas Filter Comparisons

 

Family/Grade

Emflon II 

Emflon PFR

Emflon HTPFR

HDCII

Emflon PFA

Membrane part number reference

V002

PFR

HTPFR

J

PFA

Membrane material

 

Polyvinyl fluoride (PVDF)

Polytetrafluoroethylene (PTFE)

Polytetrafluoroethylene (PTFE)

Polypropylene (PP)

Polytetrafluoroethylene (PTFE)

Support and drainage layer/ core/cage/endcap material

 

Polypropylene

 

Polypropylene

 

Polypropylene

 

Polypropylene

 

Polypropylene

Gamma Sterilizable?

Yes

No

No

No

No

Steam and Autoclave Sterilizable?

Yes

Yes

Yes

Yes

Yes

Pore size (µm)

0.2

0.2

0.2

1.2 – 10

0.2

Suitability for highly oxidative environments

 

Good

 

Very Good

 

Excellent

 

Good

 

Good

Suitability for high temperature environments

 

Good

 

Very Good

 

Excellent

 

Good

 

Good




For sterilizing-grade gas filtration in single-use systems

 

Emflon® II PVDF sterilizing-grade membrane gas filters are used in single-use systems and are validated for gamma irradiation. Emflon II filter capsules can be supplied either pre-sterilized by gamma irradiation or non-sterilized for sterilization by gamma irradiation/autoclave by the end user.

 

For sterilizing-grade gas filtration in stainless steel systems

 

Emflon® PFR PTFE sterilizing-grade membrane filter cartridges and capsules are used in nitrogen blanketing or compressed gas applications for stainless steel bioreactors and filling operations.  The hydrophobic and chemically inert filter membranes meet the FDA requirements for microbial removal to qualify as sterilizing-grade. These filters have high strength and long life under 60°C.

 

For high-temperature, ozonated-water venting and oxygen-enriched applications

 

Emflon® HTPFR PTFE sterilizing-grade membrane filter cartridges are specially designed for gas filtration in highly oxidizing applications such as oxygen enrichment of bioreactors, or process steps with temperatures above 60 °C, such as autoclaves, fermentation inlet air, aseptic packaging/ blow-fill-seal and WFI tank vents. The Emflon HTPFR cartridges have an oxidation-resistant structure that has been validated for extended use at elevated temperatures or in highly oxidizing applications.

 

Prefilter

 

HDC® II PP filters are used for prefiltration to protect sterilizing-grade filters.  They can also be used in fine particle applications where purity, reliability, and economy are critical.  All-polypropylene filter capsules and cartridges incorporate proprietary HDC II tapered pore polypropylene depth media and are available in a range of different formats. 

 

Bioburden

 

Emflon® PFA PTFE filters can be used in bioburden applications where a sterilizing-grade filter isn’t required.  These gas filter cartridges offer the highest levels of bioburden reduction, and high flow rates combined with a high filter area per 254 mm (10 in.) cartridge.

Applications

 

Application

Recommended Filter

Sterilizing-grade for single-use systems

Emflon® II

Sterilizing-grade for stainless steel systems

Emflon® PFR

Sterilizing-grade for high-temperature, ozonated-water venting, and oxygen enriched applications

Emflon® HTPFR

Prefilter for protection of sterilizing-grade gas filters

HDC® II

Bioburden reduction for high flow applications

Emflon® PFA

 


Need more help choosing the right filter? 

 

Our Scientific and Laboratory Services (SLS) team have been helping our customers optimize their processes for more than 50 years. Together with our wide range of filter membranes, we can find the right filtration solution or help to optimize your sterile filtration process. 

 

Contact us via the web form at the bottom of this page to request a consultation with one of our sterile filtration specialists to discuss your process and offer free support to help you get it right.

 

Documents

Application Notes

  • Safety Considerations for Gas Filtration in High-Temperature and Oxygen Enrichment Applications

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  • Best Practices For Successful Filter Integrity Testing Using The Water Intrusion Test (WIT) Method

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  • Identifying False Failures Using the Water Intrusion Test

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  • How to Select the Right Filter Integrity Test Instrument

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  • Sterile Vent Filtration on Ozonated Water Tanks

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  • Sterilizing Filtration of Enriched and Pure Gaseous Oxygen Employed in Cell Culture Applications

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  • Meeting Regulatory Requirements for Vent Filtration on Water For Injection (WFI) Tanks

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