Depth Filters

 

Depth filters are ideally suited for demanding prefiltration, cell harvesting, and post virus inactivation clarification processes in biopharmaceutical and biotech applications. Biotech depth filters remove cell debris and contaminants, ensuring better protection to downstream purification processes such as chromatography and sterile filtration.

Accessories Spare Parts
Accessories Spare Parts
Coalescers
Coalescers
Depth Filter Sheets
Depth Filter Sheets
Diagnostic Monitoring Equipment
Diagnostic Monitoring Equipment
Filter Capsules
Filter Capsules
Filter Cartridges
Filter Cartridges
Housings Vessels Assemblies
Housings Vessels Assemblies
Large Format Filters
Large Format Filters
Lenticular Filters
Lenticular Filters
Metal Filters
Metal Filters
Microza Hollow Fiber Modules
Microza Hollow Fiber Modules
Vent Filters
Vent Filters

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Availability

In Stock

FEATURED

Supralon™ Lube and Hydraulic Fluid Filter Elements, Removal Rating 7 μm, GlassFiber, Length 13 inches

Product ID: HC9604FRN13H
Unit of Measure
6/EA
Min Order Qty
6
Removal Rating
7 µm
Membrane Material
Glass Fiber
Poly-Fine® II, Filter Cartridges, Removal Rating 30 μm, Polypropylene, Length 10 Inches, EPDM, DOE industrial product photo

Poly-Fine® II, Filter Cartridges, Removal Rating 30 μm, Polypropylene, Length 10 Inches, EPDM, DOE industrial

Product ID: PFT3010UE
Unit of Measure
1/EA
Min Order Qty
1
Micron
30 µm
FEATURED

Supralon™ Lube and Hydraulic Fluid Filter Elements, Removal Rating 12 μm, GlassFiber, Length 8 Inches

Product ID: HC6200FRS8Z
Unit of Measure
6/EA
Min Order Qty
6
Removal Rating
12 µm
Membrane Material
Glass Fiber

SUPRAdisc SD II 300 200X300C232SPW

Product ID: 7007876
Unit of Measure
1/EA
Min Order Qty
1
1. Recommended Max. Backpressure During Backwash
0.5 bar
2. Recommended Max. Backpressure During Backwash
7.25 psid
Adaptor Type
Double Open End, Flat Gasket
Core Drainage Discs
Polypropylene
Diameter (Imperial)
12 in
Diameter (Metric)
287 mm
See All Attributes

Duo-Fine®, Filter Cartridges, Removal Rating 10 μm, Length 20 Inches

Product ID: DFPT1020ETM3
Unit of Measure
1/EA
Min Order Qty
1
Removal Rating
10 µm
Cartridge Length (Imperial)
20 in
Cartridge Length (Metric)
508 mm
Cartridge Length (Metric)
50.8 cm
End Configuration Code
M3
End Configuration
SOE flat closed end, external 222 O-rings (retrofits other manufacturers’ Code 0) 3
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This product is currently not available. Please contact us for more information.

Supralon™ Lube and Hydraulic Fluid Filter Elements, Removal Rating 7 μm, GlassFiber, Length 8 Inches

Product ID: HC7414FRN8Z
Unit of Measure
12/EA
Min Order Qty
12
Anti-Static
Yes
Beta Rating
BETA 2000
Element Series
HC7414
Family
Supralon
Filter Media
Glass Fiber
Filter Removal Rating
7 micron (Beta 2000)
See All Attributes

MCY4463J200H13

Product ID: MCY4463J200H13
Unit of Measure
12/EA
Min Order Qty
12

PF 2-30AE

Product ID: PF230AE
Unit of Measure
1/EA
Min Order Qty
1

Profile® II, Filter Cartridges, Polypropylene, Length 10 Inches, Timonium

Product ID: RM1F005H21TIMONIUM
Unit of Measure
24/EA
Min Order Qty
24
Removal Rating
0.5 µm
Membrane Material
Polypropylene
Filter Cartridge Style
RMF-style
Cartridge Length (Imperial)
10 in
Cartridge Length (Metric)
254 mm
Cartridge Length (Metric)
25.4 cm
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Supralon™ Lube and Hydraulic Fluid Filter Elements, Removal Rating 5 μm, GlassFiber, Length 13 Inches

Product ID: 0107993-KP
Unit of Measure
1/EA
Min Order Qty
1
Anti-Static
No
Beta Rating
BETA 2000
Element Series
HC9600
Family
Supralon
Filter Media
Glass Fiber
Filter Removal Rating
5 micron (Beta 2000)
See All Attributes

O-RING FLCB ORH906

Product ID: 1128053
Unit of Measure
1/EA
Min Order Qty
1

O-RING FLCB ORH139

Product ID: 1127314
Unit of Measure
1/EA
Min Order Qty
1
1,602 Items

 

 

Description

 

Pall offers a wide range of media product families of biotech depth filters to accommodate clarification applications such as monoclonal antibodies, vaccines, gene therapy, human blood plasma, and API. Pall also offers wide range of device formats to accommodate process development and single use manufacturing.

 

 

Depth Filter Comparisons

 

Specification Supracap 50 Supracap 100 Supradisc Stax
Media Grade Available in all depth filter media grades
Media Material Cellulose
Capsule Material Polypropylene
Autoclave Sterilizable 125 ºC at 30 minutes 125 ºC at 60 minutes 60 minutes at 125 ºC 2 autoclave cycles: 60 minutes at 125 ºC
Steam Sterilizable N/A N/A

125 °C (257 °F) for 30 minutes

at 0.3 bard (4.3 psid) maximum

 N/A
Maximum Differential Pressure 1.5 bar (22 psi) 2.4 bar (35 psi) 2.4 bard (35 psid) 2.4 bar (35 psi) at 25 °C – forward direction
Maximum Operating Pressure 3 bar (44 psi) @ 40 ºC 3 bar (44 psi) @ 40 ºC 80 °C (176 °F)

3.5 bar (50 psi) at 25 °C

1.0 bar (14.3 psi) at 60 °C
Effective Filter Area 22 cm2 0.025 m2 – 0.3 m2 0.3 m2 – 5 m2 0.5 m2 – 2m2
Suitable Process Scale <1-3 L 3 – 100+ L 50 – 20,000+ L 50 – 20,000+ L

 

 

Device format by process scale

 

 

Device format by process scale

 

Media grades comparison

 

 

Seitz Bio-series
  • Single layer media made of highly purified, natural/modified cellulose fibers
  • No inorganic additives such as diatomaceous earth (DE), perlite, or glass fiber
  • Low release of extractables
  • Low protein adsorption
Seitz P-Series
  • Single layer media specially developed for biotech/pharmaceutical industry, high purity medium
  • Contains inorganic additives such as diatomaceous earth (DE), perlite, or glass fiber
  • No recycled materials
  • Low virus retention
Seitz AKS-Series
  • Embedded with activated carbon
  • Suitable for decolorization and removal of other impurities
Seitz HP-Series
  • Double layer of P-Series depth filter sheets
  • Suitable for low viability/high solid containing applications

 

 

Media grade retention ratings

 

 

Media grade retention ratings

 

Shop by media grade

 

Applications

 

 

Considerations when Selecting Media
Particle Distribution Size
  • Cell size
  • Total and viable cell density
  • Cell viability
  • Lysis process
Cell Culture
  • Adherent or suspension
  • Cell line
  • Bioreactor or shake flask

 

 

Below are depth filter recommendations for common applications. Media grade can vary based on process conditions so multiple options are provided where appropriate.  Please consult a Pall expert before confirming your selection.

 

 

Applications Recommended Depth Filter

mAbs and Recombinant Protein Clarification

(Recombinant proteins produced in mammalian or insect cell lines)

Media: PDP8+PDE2

Platform: Stax Max
Gene Therapy AAV Clarification

Adherent Cell Culture

Media: V100P, PDK11, Bio10

 

Suspension Cell Culture

Media: PDK11, PDP8+Bio10
Gene Therapy LV Clarification

Adherent Cell Culture

Media: V100P

 

Suspension Cell Culture

Media: V100P, PDK11, PDP8+V100P
Microbial Fermentation Clarification

Lysed

Media: PDE2, PDH4

 

Not Lysed

Product: Stax CF Cake Filtration
Yeast Clarification Product: Stax CF Cake Filtration
Decolorization Media: AKS-Series

 

 

Depth filter media can be scaled up from process development to commercial. Proof of concept can be performed at process development by a Pall expert scale upon request.

 

 

Process Scale Recommended Device Format
Process Development Supracap 50 and Supracap 100
Pilot Scale Supracap 100 and Stax
Commercial Product Scale Stax and Supradisc

 

 

Need more help choosing the right filter? 

 

Our Scientific and Laboratory Services (SLS) team have been helping our customers optimize their processes for more than 50 years. Together with our wide range of filter membranes, we can find the right filtration solution or help to optimize your sterile filtration process. 

 

Our Process Development Services (PDS) team can reduce your development time. Our proven methods and integrated bioprocess solutions can help drive down costs and risks.

 

Request a consultation with one of our depth filtration specialists to discuss your process and offer free support to help you get it right.

 

 

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