Depth Filters

 

Depth filters are ideally suited for demanding prefiltration, cell harvesting, and post virus inactivation clarification processes in biopharmaceutical and biotech applications. Biotech depth filters remove cell debris and contaminants, ensuring better protection to downstream purification processes such as chromatography and sterile filtration.

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Sterilization Option(s)

Provided Pre-Sterilized by Gamma Irradiation

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 375 cm² EFA, 1-1½ in. sanitary flange connections, pre-sterilized by gamma irradiation product photo

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 375 cm² EFA, 1-1½ in. sanitary flange connections, pre-sterilized by gamma irradiation

Product ID: KA1EKVP1S
Unit of Measure
1/EA
Min Order Qty
1
Removal Rating
0.2 µm
Membrane Material
Polyethersulfone (PES)
Effective Filtration Area
375 cm²
Sterilization Option(s)
Provided Pre-Sterilized by Gamma Irradiation
Inlet Connection
1-1½ in (25-38 mm) sanitary flange
See All Attributes

This product is currently not available. Please contact us for more information.

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 375 cm² EFA, ½ in. hose barb connections, pre-sterilized by gamma irradiation product photo

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 375 cm² EFA, ½ in. hose barb connections, pre-sterilized by gamma irradiation

Product ID: KA1EKVP6S
Unit of Measure
1/EA
Min Order Qty
1
Removal Rating
0.2 µm
Membrane Material
Polyethersulfone (PES)
Effective Filtration Area
375 cm²
Sterilization Option(s)
Provided Pre-Sterilized by Gamma Irradiation
Inlet Connection
½ in (13 mm) hose barb
See All Attributes

This product is currently not available. Please contact us for more information.

Fluorodyne® II DFL membrane in Kleenpak™ capsule, 0.2 µm sterilizing grade, 800 cm² EFA, 1½ in. sanitary flange inlet and ½ in. hose barb outlet connections, pre-sterilized by gamma irradiation product photo

Fluorodyne® II DFL membrane in Kleenpak™ capsule, 0.2 µm sterilizing grade, 800 cm² EFA, 1½ in. sanitary flange inlet and ½ in. hose barb outlet connections, pre-sterilized by gamma irradiation

Product ID: KA2DFLP16S
Unit of Measure
1/EA
Min Order Qty
1
Removal Rating
0.2 µm
Membrane Material
Polyvinylidene fluoride (PVDF)
Sterilization Option(s)
Provided Pre-Sterilized by Gamma Irradiation
See All Attributes

This product is currently not available. Please contact us for more information.

Emflon® II membrane in Kleenpak™ capsule, 0.2 µm sterilizing grade, 380 cm² EFA, 1-1½ in. sanitary flange connections, pre-sterilized by gamma irradiation product photo

Emflon® II membrane in Kleenpak™ capsule, 0.2 µm sterilizing grade, 380 cm² EFA, 1-1½ in. sanitary flange connections, pre-sterilized by gamma irradiation

Product ID: KA1V002PV1S
Unit of Measure
1/EA
Min Order Qty
1
Membrane Material
Polyvinylidene fluoride (PVDF)
Effective Filtration Area (Metric)
380 cm²
See All Attributes
Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 750 cm² EFA, 1-1½ in. sanitary flange connections, pre-sterilized by gamma irradiation product photo

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 750 cm² EFA, 1-1½ in. sanitary flange connections, pre-sterilized by gamma irradiation

Product ID: KA2EKVP1S
Unit of Measure
1/EA
Min Order Qty
1
Removal Rating
0.2 µm
Membrane Material
Polyethersulfone (PES)
Effective Filtration Area
750 cm²
Sterilization Option(s)
Provided Pre-Sterilized by Gamma Irradiation
Inlet Connection
1-1½ in (25-38 mm) sanitary flange
See All Attributes

This product is currently not available. Please contact us for more information.

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 750 cm² EFA, ½ in. hose barb connections, pre-sterilized by gamma irradiation product photo

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 750 cm² EFA, ½ in. hose barb connections, pre-sterilized by gamma irradiation

Product ID: KA2EKVP6S
Unit of Measure
1/EA
Min Order Qty
1
Removal Rating
0.2 µm
Membrane Material
Polyethersulfone (PES)
Effective Filtration Area
750 cm²
Sterilization Option(s)
Provided Pre-Sterilized by Gamma Irradiation
Inlet Connection
½ in (13 mm) hose barb
See All Attributes

This product is currently not available. Please contact us for more information.

Emflon® II membrane in Kleenpak™ capsule, 0.2 µm sterilizing grade, 820 cm² EFA, ¼-½ in. hose barb connections, pre-sterilized by gamma irradiation product photo

Emflon® II membrane in Kleenpak™ capsule, 0.2 µm sterilizing grade, 820 cm² EFA, ¼-½ in. hose barb connections, pre-sterilized by gamma irradiation

Product ID: KA2V002PV2S
Unit of Measure
1/EA
Min Order Qty
1
Membrane Material
Polyvinylidene fluoride (PVDF)
Effective Filtration Area (Metric)
820 cm²
See All Attributes

This product is currently not available. Please contact us for more information.

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 1500 cm² EFA, 1-1½ in. sanitary flange connections, pre-sterilized by gamma irradiation product photo

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 1500 cm² EFA, 1-1½ in. sanitary flange connections, pre-sterilized by gamma irradiation

Product ID: KA3EKVP1S
Unit of Measure
1/EA
Min Order Qty
1
Removal Rating
0.2 µm
Membrane Material
Polyethersulfone (PES)
Effective Filtration Area
1500 cm²
Sterilization Option(s)
Provided Pre-Sterilized by Gamma Irradiation
Inlet Connection
1-1½ in (25-38 mm) sanitary flange
See All Attributes
Emflon® II membrane in Kleenpak™ capsule, 0.2 µm sterilizing grade, 1700 cm² EFA, ½ in. hose barb connections, pre-sterilized by gamma irradiation product photo

Emflon® II membrane in Kleenpak™ capsule, 0.2 µm sterilizing grade, 1700 cm² EFA, ½ in. hose barb connections, pre-sterilized by gamma irradiation

Product ID: KA3V002PV6S
Unit of Measure
1/EA
Min Order Qty
1
Membrane Material
Polyvinylidene fluoride (PVDF)
Effective Filtration Area (Metric)
1700 cm²
See All Attributes

This product is currently not available. Please contact us for more information.

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 1500 cm² EFA, ½ in. hose barb connections, pre-sterilized by gamma irradiation product photo

Supor® EKV membrane in Kleenpak™ capsule, 0.2 µm removal rating, 1500 cm² EFA, ½ in. hose barb connections, pre-sterilized by gamma irradiation

Product ID: KA3EKVP6S
Unit of Measure
1/EA
Min Order Qty
1
Removal Rating
0.2 µm
Membrane Material
Polyethersulfone (PES)
Effective Filtration Area
1500 cm²
Sterilization Option(s)
Provided Pre-Sterilized by Gamma Irradiation
Inlet Connection
½ in (13 mm) hose barb
See All Attributes
Emflon® II membrane in Kleenpak™ capsule, 0.2 µm sterilizing grade, 1700 cm² EFA, 1-1½ in. sanitary flange connections, pre-sterilized by gamma irradiation product photo

Emflon® II membrane in Kleenpak™ capsule, 0.2 µm sterilizing grade, 1700 cm² EFA, 1-1½ in. sanitary flange connections, pre-sterilized by gamma irradiation

Product ID: KA3V002PV1S
Unit of Measure
1/EA
Min Order Qty
1
Membrane Material
Polyvinylidene fluoride (PVDF)
Effective Filtration Area (Metric)
1700 cm²
See All Attributes

Emflon® II Membrane in Kleenpak™ Capsules serves the user's specific systematic needs. Pall offers options including gama-irradiatable, pre-sterilized and custom-made sets. All versions perform to the same top quality standard. Each unit is fully integrity testable and has the highly retentive Emflon II membrane. These capsule filters provide high air flows of both air and gas.

9 Products In Family

 

 

Description

 

Pall offers a wide range of media product families of biotech depth filters to accommodate clarification applications such as monoclonal antibodies, vaccines, gene therapy, human blood plasma, and API. Pall also offers wide range of device formats to accommodate process development and single use manufacturing.

 

 

Depth Filter Comparisons

 

Specification Supracap 50 Supracap 100 Supradisc Stax
Media Grade Available in all depth filter media grades
Media Material Cellulose
Capsule Material Polypropylene
Autoclave Sterilizable 125 ºC at 30 minutes 125 ºC at 60 minutes 60 minutes at 125 ºC 2 autoclave cycles: 60 minutes at 125 ºC
Steam Sterilizable N/A N/A

125 °C (257 °F) for 30 minutes

at 0.3 bard (4.3 psid) maximum

N/A
Maximum Differential Pressure 1.5 bar (22 psi) 2.4 bar (35 psi) 2.4 bard (35 psid) 2.4 bar (35 psi) at 25 °C – forward direction
Maximum Operating Pressure 3 bar (44 psi) @ 40 ºC 3 bar (44 psi) @ 40 ºC 80 °C (176 °F)

3.5 bar (50 psi) at 25 °C

1.0 bar (14.3 psi) at 60 °C

Effective Filter Area 22 cm2 0.025 m2 – 0.3 m2 0.3 m2 – 5 m2 0.5 m2 – 2m2
Suitable Process Scale <1-3 L 3 – 100+ L 50 – 20,000+ L 50 – 20,000+ L

 

 

Device format by process scale

 

 

 

Media grades comparison

 

 

Seitz Bio-series
  • Single layer media made of highly purified, natural/modified cellulose fibers
  • No inorganic additives such as diatomaceous earth (DE), perlite, or glass fiber
  • Low release of extractables
  • Low protein adsorption
Seitz P-Series
  • Single layer media specially developed for biotech/pharmaceutical industry, high purity medium
  • Contains inorganic additives such as diatomaceous earth (DE), perlite, or glass fiber
  • No recycled materials
  • Low virus retention
Seitz AKS-Series
  • Embedded with activated carbon
  • Suitable for decolorization and removal of other impurities
Seitz HP-Series
  • Double layer of P-Series depth filter sheets
  • Suitable for low viability/high solid containing applications

 

 

Media grade retention ratings

 

 

 

Shop by media grade

 

Applications

 

 

Considerations when Selecting Media
Particle Distribution Size
  • Cell size
  • Total and viable cell density
  • Cell viability
  • Lysis process
Cell Culture
  • Adherent or suspension
  • Cell line
  • Bioreactor or shake flask

 

 

Below are depth filter recommendations for common applications. Media grade can vary based on process conditions so multiple options are provided where appropriate.  Please consult a Pall expert before confirming your selection.

 

 

Applications Recommended Depth Filter

mAbs and Recombinant Protein Clarification

(Recombinant proteins produced in mammalian or insect cell lines)

Media: PDP8+PDE2

Platform: Stax Max

Gene Therapy AAV Clarification

Adherent Cell Culture

Media: V100P, PDK11, Bio10

 

Suspension Cell Culture

Media: PDK11, PDP8+Bio10

Gene Therapy LV Clarification

Adherent Cell Culture

Media: V100P

 

Suspension Cell Culture

Media: V100P, PDK11, PDP8+V100P

Microbial Fermentation Clarification

Lysed

Media: PDE2, PDH4

 

Not Lysed

Product: Stax CF Cake Filtration

Yeast Clarification Product: Stax CF Cake Filtration
Decolorization Media: AKS-Series

 

 

Depth filter media can be scaled up from process development to commercial. Proof of concept can be performed at process development by a Pall expert scale upon request.

 

 

Process Scale Recommended Device Format
Process Development Supracap 50 and Supracap 100
Pilot Scale Supracap 100 and Stax
Commercial Product Scale Stax and Supradisc

 

 

Need more help choosing the right filter? 

 

Our Scientific and Laboratory Services (SLS) team have been helping our customers optimize their processes for more than 50 years. Together with our wide range of filter membranes, we can find the right filtration solution or help to optimize your sterile filtration process. 

 

Our Process Development Services (PDS) team can reduce your development time. Our proven methods and integrated bioprocess solutions can help drive down costs and risks.

 

Request a consultation with one of our depth filtration specialists to discuss your process and offer free support to help you get it right.