Depth Filters

 

Depth filters are ideally suited for demanding prefiltration, cell harvesting, and post virus inactivation clarification processes in biopharmaceutical and biotech applications. Biotech depth filters remove cell debris and contaminants, ensuring better protection to downstream purification processes such as chromatography and sterile filtration.

Filter Cartridges
Filter Cartridges

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Industries

Industrial Manufacturing

Seal Material

Chloroprene

Ultipor III Glass Fiber 12 micron (Beta 1000) Chloroprene 16in 40.64cm

Product ID: HC8900FTS16P
Unit of Measure
6/EA
Min Order Qty
6
Anti-Static
No
Beta Rating
BETA 1000
Element Series
HC8900
Family
Ultipor III
Filter Media
Glass Fiber
Filter Removal Rating (μm)
12 µm
See All Attributes

Ultipor III Glass Fiber 12 micron (Beta 1000) Chloroprene 26in 66.04cm length

Product ID: HC8900FTS26P
Unit of Measure
1/EA
Min Order Qty
1
Anti-Static
No
Beta Rating
BETA 1000
Element Series
HC8900
Family
Ultipor III
Filter Media
Glass Fiber
Filter Removal Rating (μm)
12 µm
See All Attributes

Ultipor III Glass Fiber 25 micron (Beta 1000) Chloroprene 13in 33.02cm length

Product ID: HC8900FTT13P
Unit of Measure
6/EA
Min Order Qty
6
Anti-Static
No
Beta Rating
BETA 1000
Element Series
HC8900
Family
Ultipor III
Filter Media
Glass Fiber
Filter Removal Rating (μm)
25 µm
See All Attributes

Ultipor III Glass Fiber 25 micron (Beta 1000) Chloroprene 16in 40.64cm

Product ID: HC8900FTT16P
Unit of Measure
6/EA
Min Order Qty
6
Anti-Static
No
Beta Rating
BETA 1000
Element Series
HC8900
Family
Ultipor III
Filter Media
Glass Fiber
Filter Removal Rating (μm)
25 µm
See All Attributes

Ultipor III Glass Fiber 25 micron (Beta 1000) Chloroprene 4in 10.16cm length

Product ID: HC9020FTT4P
Unit of Measure
12/EA
Min Order Qty
12
Anti-Static
No
Beta Rating
BETA 1000
Element Series
HC9020
Family
Ultipor III
Filter Media
Glass Fiber
Filter Removal Rating (μm)
25 µm
See All Attributes

Supralon™ Lube and Hydraulic Elements, Removal Rating 5 μm, GlassFiber, Length 4 inches

Product ID: HC9104FRP4PYR19
Unit of Measure
12/EA
Min Order Qty
12
Anti-Static
Yes
Beta Rating
BETA 2000
Element Series
HC9104
Family
Supralon
Filter Media
Glass Fiber
Filter Removal Rating
5 micron (Beta 2000)
See All Attributes

Supralon™ Lube and Hydraulic Elements, Removal Rating 5 μm, GlassFiber, Length 8 inches

Product ID: HC9300FRP8PYV1
Unit of Measure
3/EA
Min Order Qty
3
Anti-Static
Yes
Beta Rating
BETA 2000
Element Series
HC9300
Family
Supralon
Filter Media
Glass Fiber
Filter Removal Rating
5 micron (Beta 2000)
See All Attributes

Supralon™ Lube and Hydraulic Elements, Removal Rating 5 μm, GlassFiber, Length 8 inches

Product ID: HC9600FRP8P
Unit of Measure
6/EA
Min Order Qty
6
Anti-Static
Yes
Beta Rating
BETA 2000
Element Series
HC9600
Family
Supralon
Filter Media
Glass Fiber
Filter Removal Rating
5 micron (Beta 2000)
See All Attributes

Supralon™ Lube and Hydraulic Elements, Removal Rating 12 μm, GlassFiber, Length 8 inches

Product ID: HC9600FRS8P
Unit of Measure
6/EA
Min Order Qty
6
Anti-Static
Yes
Beta Rating
BETA 2000
Element Series
HC9600
Family
Supralon
Filter Media
Glass Fiber
Filter Removal Rating
12 micron (Beta 2000)
See All Attributes

Ultipor III Glass Fiber 12 micron (Beta 1000) Chloroprene 16in 40.64cm

Product ID: HC9600FTS16P
Unit of Measure
1/EA
Min Order Qty
1
Anti-Static
No
Beta Rating
BETA 1000
Element Series
HC9600
Family
Ultipor III
Filter Media
Glass Fiber
Filter Removal Rating (μm)
12 µm
See All Attributes

Ultipor, 1200psi Duplex Hsg, 1.25in SAE Ports, 8in Length, Chloroprene Seals

Product ID: HZ8670A20SB1
Unit of Measure
1/EA
Min Order Qty
1
Inlet/Outlet Connections Type
SAE Straight Thread
Cartridge Length (Imperial)
8 in
Family
Ultipor
Pressure Rating
1200 psi
Port Size
1.25 in
Number of Cartridges
1 per side
See All Attributes

Ultipor III Glass Fiber Chloroprene

Product ID: KITELEM8900TC00001
Unit of Measure
1/EA
Min Order Qty
1
Anti-Static
No
Element Series
HC8900
Family
Ultipor III
Filter Media
Glass Fiber
Seal Material
Chloroprene
18 Items

 

 

Description

 

Pall offers a wide range of media product families of biotech depth filters to accommodate clarification applications such as monoclonal antibodies, vaccines, gene therapy, human blood plasma, and API. Pall also offers wide range of device formats to accommodate process development and single use manufacturing.

 

 

Depth Filter Comparisons

 

Specification Supracap 50 Supracap 100 Supradisc Stax
Media Grade Available in all depth filter media grades
Media Material Cellulose
Capsule Material Polypropylene
Autoclave Sterilizable 125 ºC at 30 minutes 125 ºC at 60 minutes 60 minutes at 125 ºC 2 autoclave cycles: 60 minutes at 125 ºC
Steam Sterilizable N/A N/A

125 °C (257 °F) for 30 minutes

at 0.3 bard (4.3 psid) maximum

 N/A
Maximum Differential Pressure 1.5 bar (22 psi) 2.4 bar (35 psi) 2.4 bard (35 psid) 2.4 bar (35 psi) at 25 °C – forward direction
Maximum Operating Pressure 3 bar (44 psi) @ 40 ºC 3 bar (44 psi) @ 40 ºC 80 °C (176 °F)

3.5 bar (50 psi) at 25 °C

1.0 bar (14.3 psi) at 60 °C
Effective Filter Area 22 cm2 0.025 m2 – 0.3 m2 0.3 m2 – 5 m2 0.5 m2 – 2m2
Suitable Process Scale <1-3 L 3 – 100+ L 50 – 20,000+ L 50 – 20,000+ L

 

 

Device format by process scale

 

 

Device format by process scale

 

Media grades comparison

 

 

Seitz Bio-series
  • Single layer media made of highly purified, natural/modified cellulose fibers
  • No inorganic additives such as diatomaceous earth (DE), perlite, or glass fiber
  • Low release of extractables
  • Low protein adsorption
Seitz P-Series
  • Single layer media specially developed for biotech/pharmaceutical industry, high purity medium
  • Contains inorganic additives such as diatomaceous earth (DE), perlite, or glass fiber
  • No recycled materials
  • Low virus retention
Seitz AKS-Series
  • Embedded with activated carbon
  • Suitable for decolorization and removal of other impurities
Seitz HP-Series
  • Double layer of P-Series depth filter sheets
  • Suitable for low viability/high solid containing applications

 

 

Media grade retention ratings

 

 

Media grade retention ratings

 

Shop by media grade

 

Applications

 

 

Considerations when Selecting Media
Particle Distribution Size
  • Cell size
  • Total and viable cell density
  • Cell viability
  • Lysis process
Cell Culture
  • Adherent or suspension
  • Cell line
  • Bioreactor or shake flask

 

 

Below are depth filter recommendations for common applications. Media grade can vary based on process conditions so multiple options are provided where appropriate.  Please consult a Pall expert before confirming your selection.

 

 

Applications Recommended Depth Filter

mAbs and Recombinant Protein Clarification

(Recombinant proteins produced in mammalian or insect cell lines)

Media: PDP8+PDE2

Platform: Stax Max
Gene Therapy AAV Clarification

Adherent Cell Culture

Media: V100P, PDK11, Bio10

 

Suspension Cell Culture

Media: PDK11, PDP8+Bio10
Gene Therapy LV Clarification

Adherent Cell Culture

Media: V100P

 

Suspension Cell Culture

Media: V100P, PDK11, PDP8+V100P
Microbial Fermentation Clarification

Lysed

Media: PDE2, PDH4

 

Not Lysed

Product: Stax CF Cake Filtration
Yeast Clarification Product: Stax CF Cake Filtration
Decolorization Media: AKS-Series

 

 

Depth filter media can be scaled up from process development to commercial. Proof of concept can be performed at process development by a Pall expert scale upon request.

 

 

Process Scale Recommended Device Format
Process Development Supracap 50 and Supracap 100
Pilot Scale Supracap 100 and Stax
Commercial Product Scale Stax and Supradisc

 

 

Need more help choosing the right filter? 

 

Our Scientific and Laboratory Services (SLS) team have been helping our customers optimize their processes for more than 50 years. Together with our wide range of filter membranes, we can find the right filtration solution or help to optimize your sterile filtration process. 

 

Our Process Development Services (PDS) team can reduce your development time. Our proven methods and integrated bioprocess solutions can help drive down costs and risks.

 

Request a consultation with one of our depth filtration specialists to discuss your process and offer free support to help you get it right.

 

 

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